↓ Skip to main content

Successful rechallenge with clozapine after treatment associated eosinophilia

Overview of attention for article published in Australasian Psychiatry, July 2016
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
12 Dimensions

Readers on

mendeley
33 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Successful rechallenge with clozapine after treatment associated eosinophilia
Published in
Australasian Psychiatry, July 2016
DOI 10.1177/1039856216654399
Pubmed ID
Authors

Peter A McArdle, Dan J Siskind, Uday Kolur, Stephen Parker, Nicole Korman, Subramanian Purushothaman

Abstract

Eosinophilia has been associated with the use of clozapine. Where clozapine associated eosinophilia develops, and is associated with organ specific damage, clozapine is usually ceased. In cases of treatment associated eosinophilia without evidence of organ specific damage, clozapine would also typically be withdrawn. There are small numbers of reports in the literature describing patients who have had a successful rechallenge of clozapine having previously stopped treatment due to eosinophilia without associated organ specific inflammation. We report the case of a man who underwent a successful retrial of clozapine. Case from authors' clinical practice reviewed. We present the case of a young man with treatment resistant schizophrenia who underwent a successful re-challenge of clozapine, having previously ceased treatment due to an eosinophilia associated with treatment. We believe that the current report provides further evidence that it may be unnecessary to cease treatment in all patients who develop an eosinophilia without organ dysfunction whilst on clozapine. Furthermore, where clozapine has been ceased due to an eosinophilia without evidence of organ specific inflammation, clozapine rechallenge with increased haematological monitoring should be considered.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 9%
Other 3 9%
Student > Bachelor 3 9%
Researcher 3 9%
Student > Doctoral Student 2 6%
Other 7 21%
Unknown 12 36%
Readers by discipline Count As %
Medicine and Dentistry 10 30%
Psychology 3 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Nursing and Health Professions 2 6%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 2 6%
Unknown 13 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 November 2022.
All research outputs
#20,199,352
of 24,832,302 outputs
Outputs from Australasian Psychiatry
#1,035
of 1,737 outputs
Outputs of similar age
#280,356
of 362,155 outputs
Outputs of similar age from Australasian Psychiatry
#77
of 119 outputs
Altmetric has tracked 24,832,302 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,737 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 362,155 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 119 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.