Title |
Molecular Markers Useful for Intraspecies Subtyping and Strain Differentiation of Dermatophytes
|
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Published in |
Mycopathologia, July 2016
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DOI | 10.1007/s11046-016-0041-4 |
Pubmed ID | |
Authors |
Takashi Mochizuki, Kiminobu Takeda, Kazushi Anzawa |
Abstract |
Dermatophytosis is a very common skin disorder and the most frequent infection encountered by practicing dermatologists. The identification, pathogenicity, biology, and epidemiology of dermatophytes, the causative agents of dermatophytosis, are of interest for both dermatologists and medical mycologists. Recent advances in molecular methods have provided new techniques for identifying dermatophytes, including intraspecies variations. Intraspecies subtyping and strain differentiation have made possible the tracking of infections, the identification of common sources of infections, recurrence or reinfection after treatment, and analysis of strain virulence and drug resistance. This review describes molecular methods of intraspecies subtyping and strain differentiation, including analyses of mitochondrial DNA and non-transcribed spacer regions of ribosomal RNA genes, random amplification of polymorphic DNA, and microsatellite markers, along with their advantages and limitations. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 31 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 10 | 32% |
Researcher | 4 | 13% |
Student > Bachelor | 2 | 6% |
Professor | 2 | 6% |
Student > Ph. D. Student | 2 | 6% |
Other | 5 | 16% |
Unknown | 6 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 26% |
Immunology and Microbiology | 6 | 19% |
Agricultural and Biological Sciences | 5 | 16% |
Veterinary Science and Veterinary Medicine | 2 | 6% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Other | 3 | 10% |
Unknown | 5 | 16% |