Title |
Rapid molecular diagnosis of infective aortic valve endocarditis caused by Coxiella burnetii
|
---|---|
Published in |
Infection, June 2016
|
DOI | 10.1007/s15010-016-0916-9 |
Pubmed ID | |
Authors |
Oliver Kumpf, Pascal Dohmen, Martin Ertmer, Fabian Knebel, Alexandra Wiessner, Judith Kikhney, Annette Moter, Sascha Treskatsch |
Abstract |
We describe a case of Q-fever endocarditis with severe destruction of the aortic valve with perivalvular abscess formation and cardiac failure. The patient needed urgent operative treatment and postoperative critical care. All specimens sent for microbiological examination were negative. Molecular analysis, including fluorescence in situ hybridization of aortic valve tissue combined with PCR and sequencing, led to the correct diagnosis and to appropriate anti-infective treatment. The patient subsequently recovered from complex cardiovascular surgery. This is the first report on Q-fever endocarditis that was rapidly diagnosed using these methods. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 4 | 14% |
Student > Ph. D. Student | 4 | 14% |
Lecturer | 3 | 11% |
Student > Doctoral Student | 3 | 11% |
Student > Bachelor | 3 | 11% |
Other | 8 | 29% |
Unknown | 3 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 20 | 71% |
Biochemistry, Genetics and Molecular Biology | 2 | 7% |
Agricultural and Biological Sciences | 1 | 4% |
Veterinary Science and Veterinary Medicine | 1 | 4% |
Unknown | 4 | 14% |