Title |
The similarity of Type 1 autoimmune pancreatitis to pancreatic ductal adenocarcinoma with significant IgG4-positive plasma cell infiltration
|
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Published in |
Journal of Gastroenterology, October 2012
|
DOI | 10.1007/s00535-012-0677-x |
Pubmed ID | |
Authors |
Yuri Fukui, Kazushige Uchida, Kimi Sumimoto, Takeo Kusuda, Hideaki Miyoshi, Masanori Koyabu, Tsukasa Ikeura, Yutaku Sakaguchi, Masaaki Shimatani, Toshiro Fukui, Mitsunobu Matsushita, Makoto Takaoka, Akiyoshi Nishio, Nobuaki Shikata, Noriko Sakaida, Yoshiko Uemura, Sohei Satoi, A-hon Kwon, Kazuichi Okazaki |
Abstract |
High serum immunoglobulin G4 (IgG4) levels and infiltration of IgG4-positive cells are characteristic of Type 1 autoimmune pancreatitis (AIP). We previously reported that increased regulatory T cells (Tregs) may regulate IgG4 production in AIP. Although an increased serum IgG4 concentration is observed in some patients with pancreatic ductal adenocarcinoma (PDA), clarification is still necessary. We have therefore studied the correlations between IgG4-positive cells and Tregs in patients with PDA. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 6% |
Unknown | 17 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 6 | 33% |
Student > Bachelor | 3 | 17% |
Other | 2 | 11% |
Professor | 2 | 11% |
Professor > Associate Professor | 2 | 11% |
Other | 2 | 11% |
Unknown | 1 | 6% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 78% |
Nursing and Health Professions | 1 | 6% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Unknown | 2 | 11% |