| Title |
Maternal and cord blood adiponectin levels in relation to post-natal body size in infants in the first year of life: a prospective study
|
|---|---|
| Published in |
BMC Pregnancy and Childbirth, July 2016
|
| DOI | 10.1186/s12884-016-0978-9 |
| Pubmed ID | |
| Authors |
Zhe-qing Zhang, Qing-gui Lu, Jie Huang, Chang-ya Jiao, Shao-ming Huang, Li-mei Mao |
| Abstract |
Adiponectin is an adipocyte hormone involved in energy homeostasis and metabolism. However, its role in early infancy is poorly understood. We recruited a total of 443 pregnant women and their children in this prospective study. Cord blood samples were successfully obtained from 331 neonates. Maternal and umbilical blood serum adiponectin were measured. The weight-, height- and BMI-for-age Z scores of infants at birth and at 3, 6 and 12 months of age were assessed. Multiple linear regression analysis indicated that cord blood but not maternal serum adiponectin was positively associated with all of the anthropometric measures at birth (P < 0.01). Using Generalized Estimating Equation model after adjustment for sex, time, maternal age, gestational age, prepregnancy BMI, weight gain during pregnancy, maternal education, parity, history of miscarriage and mode of delivery, for every 1-μg/ml increment of maternal serum adiponectin, the height-for-age Z score during the first year of life increased by 0.026 (P =0.013) on average, and the height-for-age Z score of infants in the highest quartile of maternal serum adiponectin was 0.270 (95 % CI: 0.013-0.527) higher than those in the lowest quartile. The changes in weight-for-age Z score from birth decreased by 0.67 × 10(-2) on average with every 1-μg/ml additional increase of cord blood adiponectin (P = 0.047). The infants in the highest quartile of cord blood adiponectin showed a -0.368 (95 % CI, -0.701--0.035) decrease in weight-for-age Z score change from birth compared with those in the lowest quartile. Cord blood adiponectin concentration is a determinant of infant birth size and weight gain in the first year of life. Circulating maternal adiponectin during pregnancy may predict postnatal height growth. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Ireland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Poland | 1 | 2% |
| Unknown | 46 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 9 | 19% |
| Student > Postgraduate | 5 | 11% |
| Student > Bachelor | 5 | 11% |
| Unspecified | 3 | 6% |
| Researcher | 3 | 6% |
| Other | 8 | 17% |
| Unknown | 14 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 9 | 19% |
| Psychology | 5 | 11% |
| Nursing and Health Professions | 4 | 9% |
| Social Sciences | 4 | 9% |
| Veterinary Science and Veterinary Medicine | 3 | 6% |
| Other | 8 | 17% |
| Unknown | 14 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 July 2016.
All research outputs
#20,336,031
of 22,881,154 outputs
Outputs from BMC Pregnancy and Childbirth
#3,809
of 4,210 outputs
Outputs of similar age
#320,088
of 365,593 outputs
Outputs of similar age from BMC Pregnancy and Childbirth
#86
of 96 outputs
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