| Title |
Application value of laboratory indexes in the differential diagnosis of Henoch–Schoenlein purpura
|
|---|---|
| Published in |
Zeitschrift für Rheumatologie, July 2016
|
| DOI | 10.1007/s00393-016-0108-0 |
| Pubmed ID | |
| Authors |
W.-X. Shao, Q. Ye, X.-J. Wang |
| Abstract |
The aim of this study was to explore the value of laboratory indexes in the differential diagnosis of Henoch-Schoenlein purpura (HSP). Patients with HSP hospitalized at the Children's Hospital of Zhejiang University School of Medicine between January 2010 and December 2014 were enrolled in this prospective study. In addition, septic patients with rash and patients with urticaria, simple hematuria, and acute appendicitis hospitalized during the same period were selected at random as differential diagnosis subjects, and healthy children were selected as normal controls. The levels of IgA, D‑dimer, fibrinogen (FIB), and platelet (PLT) and the platelet distribution width (PDW) of these individuals were tested and analyzed, and the ROC curve was used to determine the applicability of these indexes to differentiate between patients with HSP and other diseases easily confused with HSP, as well as to determine the efficacy of combined diagnosis. There were remarkable differences in the levels of FIB, D‑dimer, IgA, PLT, and PDW among patients with HSP, sepsis patients with rash, patients with urticaria, simple hematuria, or acute appendicitis and healthy children (P < 0.01). The levels of IgA, D‑dimer, and PLT can be applied separately for the differential diagnosis of HSP, and these indexes and FIB can be combined appropriately to improve the diagnostic efficacy. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Romania | 1 | 14% |
| Taiwan | 1 | 14% |
| Argentina | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 71% |
| Practitioners (doctors, other healthcare professionals) | 1 | 14% |
| Scientists | 1 | 14% |
Mendeley readers
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 1 | 100% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 1 | 100% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 July 2016.
All research outputs
#13,240,961
of 22,881,964 outputs
Outputs from Zeitschrift für Rheumatologie
#204
of 446 outputs
Outputs of similar age
#193,354
of 364,407 outputs
Outputs of similar age from Zeitschrift für Rheumatologie
#5
of 10 outputs
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So far Altmetric has tracked 446 research outputs from this source. They receive a mean Attention Score of 3.1. This one has gotten more attention than average, scoring higher than 53% of its peers.
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