| Title |
Case report: on the use of the HID-Ion AmpliSeq™ Ancestry Panel in a real forensic case
|
|---|---|
| Published in |
International Journal of Legal Medicine, July 2016
|
| DOI | 10.1007/s00414-016-1425-1 |
| Pubmed ID | |
| Authors |
C. Hollard, C. Keyser, T. Delabarde, A. Gonzalez, C. Vilela Lamego, V. Zvénigorosky, B. Ludes |
| Abstract |
In the absence of any other conclusive forensic evidence, DNA profiling is the method of choice for body identification. This study focuses on the case of a carbonized corpse whose complete autosomal short tandem repeat (STR) profile could not lead to direct identification by the investigators. To assist in the progress of investigation, we endeavoured to determine the biogeographical origin and eye colour of the deceased individual. Along with Y chromosome and mitochondrial DNA analyses, we applied a next-generation sequencing (NGS) approach to the study of ancestry informative markers (AIMs) using the HID-Ion AmpliSeq™ Ancestry Panel launched by Thermo Fisher Scientific. This work gave us the opportunity to test this new technology in a real forensic case. Although this study highlights the benefits of such a combined approach, as it markedly improves the specificity of the biogeographical profile, it also underlines the need for the accurate characterization of a larger collection of reference populations and the necessity of caution in data interpretation. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 55 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 11 | 20% |
| Student > Master | 7 | 13% |
| Student > Bachelor | 6 | 11% |
| Student > Postgraduate | 5 | 9% |
| Student > Ph. D. Student | 4 | 7% |
| Other | 8 | 15% |
| Unknown | 14 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 23 | 42% |
| Agricultural and Biological Sciences | 10 | 18% |
| Medicine and Dentistry | 3 | 5% |
| Unspecified | 1 | 2% |
| Arts and Humanities | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 16 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2017.
All research outputs
#14,268,650
of 22,881,964 outputs
Outputs from International Journal of Legal Medicine
#775
of 2,072 outputs
Outputs of similar age
#214,791
of 365,664 outputs
Outputs of similar age from International Journal of Legal Medicine
#5
of 18 outputs
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So far Altmetric has tracked 2,072 research outputs from this source. They receive a mean Attention Score of 4.6. This one has gotten more attention than average, scoring higher than 59% of its peers.
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We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.