| Title |
Dendritic cells as gatekeepers of tolerance
|
|---|---|
| Published in |
Seminars in Immunopathology, July 2016
|
| DOI | 10.1007/s00281-016-0583-z |
| Pubmed ID | |
| Authors |
Ari Waisman, Dominika Lukas, Björn E. Clausen, Nir Yogev |
| Abstract |
Dendritic cells (DC) are unique hematopoietic cells, linking innate and adaptive immune responses. In particular, they are considered as the most potent antigen presenting cells, governing both T cell immunity and tolerance. In view of their exceptional ability to present antigen and to interact with T cells, DC play distinct roles in shaping T cell development, differentiation and function. The outcome of the DC-T cell interaction is determined by the state of DC maturation, the type of DC subset, the cytokine microenvironment and the tissue location. Both regulatory T cells (Tregs) and DC are indispensable for maintaining central and peripheral tolerance. Over the past decade, accumulating data indicate that DC critically contribute to Treg differentiation and homeostasis. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 282 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | <1% |
| Unknown | 281 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 52 | 18% |
| Student > Bachelor | 43 | 15% |
| Researcher | 27 | 10% |
| Student > Master | 25 | 9% |
| Student > Doctoral Student | 23 | 8% |
| Other | 27 | 10% |
| Unknown | 85 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 62 | 22% |
| Biochemistry, Genetics and Molecular Biology | 46 | 16% |
| Medicine and Dentistry | 28 | 10% |
| Agricultural and Biological Sciences | 18 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 3% |
| Other | 28 | 10% |
| Unknown | 91 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 August 2021.
All research outputs
#7,229,289
of 23,577,654 outputs
Outputs from Seminars in Immunopathology
#203
of 562 outputs
Outputs of similar age
#120,473
of 367,775 outputs
Outputs of similar age from Seminars in Immunopathology
#3
of 9 outputs
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So far Altmetric has tracked 562 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has gotten more attention than average, scoring higher than 60% of its peers.
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