Title |
Augmenting Cognitive Behavior Therapy for School Refusal with Fluoxetine: A Randomized Controlled Trial
|
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Published in |
Child Psychiatry & Human Development, August 2016
|
DOI | 10.1007/s10578-016-0675-y |
Pubmed ID | |
Authors |
Glenn A. Melvin, Amanda L. Dudley, Michael S. Gordon, Ester Klimkeit, Eleonora Gullone, John Taffe, Bruce J. Tonge |
Abstract |
This study investigates whether the augmentation of cognitive behavior therapy (CBT) with fluoxetine improves outcomes in anxious school refusing adolescents (11-16.5 years). Sixty-two participants were randomly allocated to CBT alone, CBT + fluoxetine or CBT + placebo. All treatments were well tolerated; with one suicide-attempt in the CBT + placebo group. All groups improved significantly on primary (school attendance) and secondary outcome measures (anxiety, depression, self-efficacy and clinician-rated global functioning); with gains largely maintained at 6-months and 1-year. Few participants were anxiety disorder free after acute treatment. During the follow-up period anxiety and depressive disorders continued to decline whilst school attendance remained stable, at around 54 %. The only significant between-group difference was greater adolescent-reported treatment satisfaction in the CBT + fluoxetine group than the CBT alone group. These results indicate the chronicity of school refusal, and the need for future research into how to best improve school attendance rates. |
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United Kingdom | 1 | 100% |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
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Colombia | 1 | <1% |
Unknown | 166 | 99% |
Demographic breakdown
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Student > Master | 24 | 14% |
Researcher | 23 | 14% |
Student > Ph. D. Student | 13 | 8% |
Student > Bachelor | 13 | 8% |
Student > Doctoral Student | 12 | 7% |
Other | 29 | 17% |
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Agricultural and Biological Sciences | 3 | 2% |
Other | 13 | 8% |
Unknown | 60 | 36% |