Title |
Synergies between assisted reproduction technologies and functional genomics
|
---|---|
Published in |
Genetics Selection Evolution, August 2016
|
DOI | 10.1186/s12711-016-0231-z |
Pubmed ID | |
Authors |
Pasqualino Loi, Paola Toschi, Federica Zacchini, Grazyna Ptak, Pier A. Scapolo, Emanuele Capra, Alessandra Stella, Paolo Ajmone Marsan, John L. Williams |
Abstract |
This review, is a synopsis of advanced reproductive technologies in farm animals, including the discussion of their limiting factors as revealed by the study of offspring derived from embryos produced in vitro and through cloning. These studies show that the problems of epigenetic mis-programming, which were reported in the initial stages of assisted reproduction, still persist. The importance of whole-genome analyses, including the methylome and transcriptome, in improving embryo biotechnologies in farm animals, are discussed. Genome editing approaches for the improvement of economically-relevant traits in farm animals are also described. Efficient farm animal embryo biotechnologies, including cloning and the most recent technologies such as genome editing, will effectively complement the latest strategies to accelerate genetic improvement of farm animals. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 33% |
France | 1 | 17% |
Unknown | 3 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 17% |
Scientists | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 51 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 13 | 25% |
Student > Bachelor | 7 | 14% |
Student > Ph. D. Student | 7 | 14% |
Student > Master | 6 | 12% |
Student > Doctoral Student | 4 | 8% |
Other | 7 | 14% |
Unknown | 7 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 18 | 35% |
Veterinary Science and Veterinary Medicine | 7 | 14% |
Biochemistry, Genetics and Molecular Biology | 7 | 14% |
Medicine and Dentistry | 3 | 6% |
Engineering | 2 | 4% |
Other | 2 | 4% |
Unknown | 12 | 24% |