| Title |
The global threat of Zika virus to pregnancy: epidemiology, clinical perspectives, mechanisms, and impact
|
|---|---|
| Published in |
BMC Medicine, August 2016
|
| DOI | 10.1186/s12916-016-0660-0 |
| Pubmed ID | |
| Authors |
Phillipe Boeuf, Heidi E. Drummer, Jack S. Richards, Michelle J. L. Scoullar, James G. Beeson |
| Abstract |
Zika virus (ZIKV) is a mosquito-borne flavivirus that has newly emerged as a significant global threat, especially to pregnancy. Recent major outbreaks in the Pacific and in Central and South America have been associated with an increased incidence of microcephaly and other abnormalities of the central nervous system in neonates. The causal link between ZIKV infection during pregnancy and microcephaly is now strongly supported. Over 2 billion people live in regions conducive to ZIKV transmission, with ~4 million infections in the Americas predicted for 2016. Given the scale of the current pandemic and the serious and long-term consequences of infection during pregnancy, the impact of ZIKV on health services and affected communities could be enormous. This further highlights the need for a rapid global public health and research response to ZIKV to limit and prevent its impact through the development of therapeutics, vaccines, and improved diagnostics. Here we review the epidemiology of ZIKV; the threat to pregnancy; the clinical consequences and broader impact of ZIKV infections; and the virus biology underpinning new interventions, diagnostics, and insights into the mechanisms of disease. |
X Demographics
The data shown below were collected from the profiles of 43 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 9 | 21% |
| United Kingdom | 5 | 12% |
| Ireland | 2 | 5% |
| Australia | 2 | 5% |
| Brazil | 2 | 5% |
| Spain | 1 | 2% |
| Canada | 1 | 2% |
| India | 1 | 2% |
| South Africa | 1 | 2% |
| Other | 2 | 5% |
| Unknown | 17 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 28 | 65% |
| Scientists | 8 | 19% |
| Practitioners (doctors, other healthcare professionals) | 5 | 12% |
| Science communicators (journalists, bloggers, editors) | 2 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 385 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | <1% |
| Spain | 1 | <1% |
| Saint Kitts and Nevis | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 380 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 99 | 26% |
| Student > Master | 79 | 21% |
| Researcher | 36 | 9% |
| Student > Ph. D. Student | 30 | 8% |
| Student > Postgraduate | 22 | 6% |
| Other | 69 | 18% |
| Unknown | 50 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 92 | 24% |
| Agricultural and Biological Sciences | 47 | 12% |
| Nursing and Health Professions | 41 | 11% |
| Biochemistry, Genetics and Molecular Biology | 36 | 9% |
| Computer Science | 28 | 7% |
| Other | 80 | 21% |
| Unknown | 61 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 39. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2020.
All research outputs
#1,022,865
of 24,833,004 outputs
Outputs from BMC Medicine
#717
of 3,861 outputs
Outputs of similar age
#20,107
of 375,921 outputs
Outputs of similar age from BMC Medicine
#8
of 44 outputs
Altmetric has tracked 24,833,004 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,861 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.2. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 375,921 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.