| Title |
The correlation between Toxoplasma gondii infection and prenatal depression in pregnant women
|
|---|---|
| Published in |
European Journal of Clinical Microbiology & Infectious Diseases, August 2016
|
| DOI | 10.1007/s10096-016-2734-5 |
| Pubmed ID | |
| Authors |
M. Nourollahpour Shiadeh, A. Rostami, B. D. Pearce, M. Gholipourmalekabadi, D. J. Newport, M. Danesh, S. Mehravar, S. J. Seyyedtabaei |
| Abstract |
Previous studies have demonstrated that latent toxoplasmosis is associated with neuropsychiatric disorders. We evaluated the correlation between Toxoplasma gondii infection and prenatal depression. In this case-control study, we enrolled 116 depressed pregnant women and 244 healthy controls. The Edinburgh Postpartum Depression Scale (EPDS) was used to evaluate the depression symptom severity in study participants. All participants were screened for the anti-Toxoplasma IgG by enzyme-linked immunosorbent assay. Seroprevalence of T. gondii did not significantly differ between the depressed pregnant women and healthy controls (OR = 1.4; 95 % CI = 0.9-2.19; P = 0.142). T. gondii IgG titer was significantly higher in depressed women (18.6 ± 10.9 IUs) than those in the control group (13.6 ± 8.1 IUs) (z = -5.36, P < 0.001). The T. gondii-positive depressed women showed a positive correlation of T. gondii IgG titer with the EPDS scores (r = 0.52; P < 0.01). The mean EPDS score was also significantly higher in the T. gondii-positive depressed women (20.7 ± 2.7) compared with the controls (18.36 ± 2.7) (P < 0.001). The results obtained from the current study revealed that T. gondii infection might affect susceptibility to depression and severity of depressive symptoms in pregnant women, particularly in those patients who have high antibody titers. Further study is required to fully elucidate the characteristics and mechanisms of this association. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 51 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 9 | 18% |
| Other | 5 | 10% |
| Student > Bachelor | 5 | 10% |
| Student > Postgraduate | 4 | 8% |
| Student > Ph. D. Student | 4 | 8% |
| Other | 10 | 20% |
| Unknown | 14 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 9 | 18% |
| Neuroscience | 6 | 12% |
| Agricultural and Biological Sciences | 6 | 12% |
| Environmental Science | 2 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
| Other | 8 | 16% |
| Unknown | 18 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2016.
All research outputs
#20,337,210
of 22,882,389 outputs
Outputs from European Journal of Clinical Microbiology & Infectious Diseases
#2,408
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Outputs of similar age
#319,398
of 364,241 outputs
Outputs of similar age from European Journal of Clinical Microbiology & Infectious Diseases
#35
of 49 outputs
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