Title |
Neural Mechanisms of Improvements in Social Motivation After Pivotal Response Treatment: Two Case Studies
|
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Published in |
Journal of Autism and Developmental Disorders, October 2012
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DOI | 10.1007/s10803-012-1683-9 |
Pubmed ID | |
Authors |
Avery C. Voos, Kevin A. Pelphrey, Jonathan Tirrell, Danielle Z. Bolling, Brent Vander Wyk, Martha D. Kaiser, James C. McPartland, Fred R. Volkmar, Pamela Ventola |
Abstract |
Pivotal response treatment (PRT) is an empirically validated behavioral treatment that has widespread positive effects on communication, behavior, and social skills in young children with autism spectrum disorder (ASD). For the first time, functional magnetic resonance imaging was used to identify the neural correlates of successful response to PRT in two young children with ASD. Baseline measures of social communication, adaptive behavior, eye tracking and neural response to social stimuli were taken prior to treatment and after 4 months of PRT. Both children showed striking gains on behavioral measures and also showed increased activation to social stimuli in brain regions utilized by typically developing children. These results suggest that neural systems supporting social perception are malleable through implementation of PRT. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 2 | 18% |
Colombia | 1 | 9% |
Canada | 1 | 9% |
United States | 1 | 9% |
Unknown | 6 | 55% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 10 | 91% |
Scientists | 1 | 9% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | <1% |
Netherlands | 1 | <1% |
Italy | 1 | <1% |
Canada | 1 | <1% |
Brazil | 1 | <1% |
Spain | 1 | <1% |
Taiwan | 1 | <1% |
Unknown | 222 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 41 | 18% |
Student > Master | 36 | 16% |
Researcher | 31 | 13% |
Student > Bachelor | 27 | 12% |
Student > Doctoral Student | 18 | 8% |
Other | 35 | 15% |
Unknown | 42 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 105 | 46% |
Medicine and Dentistry | 17 | 7% |
Social Sciences | 17 | 7% |
Neuroscience | 15 | 7% |
Agricultural and Biological Sciences | 6 | 3% |
Other | 19 | 8% |
Unknown | 51 | 22% |