Title |
Maternal Exposure to Occupational Asthmagens During Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development
|
---|---|
Published in |
Journal of Autism and Developmental Disorders, August 2016
|
DOI | 10.1007/s10803-016-2882-6 |
Pubmed ID | |
Authors |
Alison B. Singer, Gayle C. Windham, Lisa A. Croen, Julie L. Daniels, Brian K. Lee, Yinge Qian, Diana E. Schendel, M. Daniele Fallin, Igor Burstyn |
Abstract |
Maternal immune activity has been linked to children with autism spectrum disorder (ASD). We examined maternal occupational exposure to asthma-causing agents during pregnancy in relation to ASD risk. Our sample included 463 ASD cases and 710 general population controls from the Study to Explore Early Development whose mothers reported at least one job during pregnancy. Asthmagen exposure was estimated from a published job-exposure matrix. The adjusted odds ratio for ASD comparing asthmagen-exposed to unexposed was 1.39 (95 % CI 0.96-2.02). Maternal workplace asthmagen exposure was not associated with ASD risk in this study, but this result does not exclude some involvement of maternal exposure to asthma-causing agents in ASD. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 25% |
Canada | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 91 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 16 | 18% |
Researcher | 11 | 12% |
Student > Ph. D. Student | 11 | 12% |
Student > Bachelor | 11 | 12% |
Student > Doctoral Student | 8 | 9% |
Other | 12 | 13% |
Unknown | 22 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 20% |
Psychology | 17 | 19% |
Nursing and Health Professions | 8 | 9% |
Social Sciences | 6 | 7% |
Immunology and Microbiology | 2 | 2% |
Other | 15 | 16% |
Unknown | 25 | 27% |