Title |
Elite endurance athletes and the ACE I allele – the role of genes in athletic performance
|
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Published in |
Human Genetics, July 1998
|
DOI | 10.1007/s004390050781 |
Pubmed ID | |
Authors |
George Gayagay, Bing Yu, Brett Hambly, Tanya Boston, Alan Hahn, David S. Celermajer, R. J. Trent |
Abstract |
Genetic markers that might contribute to the making of an elite athlete have not been identified. Potential candidate genes might be found in the renin-angiotensin pathway, which plays a key role in the regulation of both cardiac and vascular physiology. In this study, DNA polymorphisms derived from the angiotensin converting enzyme (ACE), the angiotensin type 1 receptor (AT1) and the angiotensin type 2 receptor (AT2) were studied in 64 Australian national rowers. Compared with a normal population, the rowers had an excess of the ACE I allele (P<0.02) and the ACE II genotype (P=0.03). The ACE I allele is a genetic marker that might be associated with athletic excellence. It is proposed that the underlying mechanism relates to a healthier cardiovascular system. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 4 | 3% |
Germany | 1 | <1% |
Unknown | 146 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 33 | 22% |
Student > Master | 27 | 18% |
Student > Ph. D. Student | 18 | 12% |
Researcher | 13 | 9% |
Professor | 6 | 4% |
Other | 24 | 16% |
Unknown | 30 | 20% |
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---|---|---|
Sports and Recreations | 42 | 28% |
Agricultural and Biological Sciences | 25 | 17% |
Medicine and Dentistry | 17 | 11% |
Biochemistry, Genetics and Molecular Biology | 15 | 10% |
Nursing and Health Professions | 8 | 5% |
Other | 13 | 9% |
Unknown | 31 | 21% |