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Synthetic constructs in/for the environment: Managing the interplay between natural and engineered Biology

Overview of attention for article published in Febs Letters, February 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
1 news outlet
policy
1 policy source
twitter
9 X users
patent
3 patents

Citations

dimensions_citation
78 Dimensions

Readers on

mendeley
205 Mendeley
citeulike
3 CiteULike
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Title
Synthetic constructs in/for the environment: Managing the interplay between natural and engineered Biology
Published in
Febs Letters, February 2012
DOI 10.1016/j.febslet.2012.02.022
Pubmed ID
Authors

Markus Schmidt, Víctor de Lorenzo

Abstract

The plausible release of deeply engineered or even entirely synthetic/artificial microorganisms raises the issue of their intentional (e.g. bioremediation) or accidental interaction with the Environment. Containment systems designed in the 1980s-1990s for limiting the spread of genetically engineered bacteria and their recombinant traits are still applicable to contemporary Synthetic Biology constructs. Yet, the ease of DNA synthesis and the uncertainty on how non-natural properties and strains could interplay with the existing biological word poses yet again the challenge of designing safe and efficacious firewalls to curtail possible interactions. Such barriers may include xeno-nucleic acids (XNAs) instead of DNA as information-bearing molecules, rewriting the genetic code to make it non-understandable by the existing gene expression machineries, and/or making growth dependent on xenobiotic chemicals.

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 205 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 5 2%
United States 4 2%
Spain 2 <1%
Denmark 2 <1%
Ireland 1 <1%
India 1 <1%
France 1 <1%
Germany 1 <1%
Netherlands 1 <1%
Other 1 <1%
Unknown 186 91%

Demographic breakdown

Readers by professional status Count As %
Researcher 49 24%
Student > Ph. D. Student 37 18%
Student > Bachelor 29 14%
Student > Master 27 13%
Other 12 6%
Other 32 16%
Unknown 19 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 97 47%
Biochemistry, Genetics and Molecular Biology 39 19%
Environmental Science 8 4%
Chemistry 8 4%
Engineering 6 3%
Other 25 12%
Unknown 22 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 26. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 August 2022.
All research outputs
#1,460,133
of 25,373,627 outputs
Outputs from Febs Letters
#102
of 14,373 outputs
Outputs of similar age
#7,605
of 169,012 outputs
Outputs of similar age from Febs Letters
#1
of 64 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,373 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,012 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 64 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.