Title |
Diagnosis, prevention, and management of bleeding episodes in Philadelphia-negative myeloproliferative neoplasms: recommendations by the Hemostasis Working Party of the German Society of Hematology and Medical Oncology (DGHO) and the Society of Thrombosis and Hemostasis Research (GTH)
|
---|---|
Published in |
Annals of Hematology, February 2016
|
DOI | 10.1007/s00277-016-2621-2 |
Pubmed ID | |
Authors |
Iris Appelmann, Stephan Kreher, Stefani Parmentier, Hans-Heinrich Wolf, Guido Bisping, Martin Kirschner, Frauke Bergmann, Kristina Schilling, Tim H. Brümmendorf, Petro E. Petrides, Andreas Tiede, Axel Matzdorff, Martin Griesshammer, Hanno Riess, Steffen Koschmieder |
Abstract |
Philadelphia-negative myeloproliferative neoplasms (Ph-negative MPN) comprise a heterogeneous group of chronic hematologic malignancies. The quality of life, morbidity, and mortality of patients with MPN are primarily affected by disease-related symptoms, thromboembolic and hemorrhagic complications, and progression to myelofibrosis and acute leukemia. Major bleeding represents a common and important complication in MPN, and the incidence of such bleeding events will become even more relevant in the future due to the increasing disease prevalence and survival of MPN patients. This review discusses the causes, differential diagnoses, prevention, and management of bleeding episodes in patients with MPN, aiming at defining updated standards of care in these often challenging situations. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 94 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 11 | 12% |
Student > Ph. D. Student | 11 | 12% |
Researcher | 9 | 10% |
Student > Master | 8 | 9% |
Student > Bachelor | 7 | 7% |
Other | 21 | 22% |
Unknown | 27 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 47 | 50% |
Biochemistry, Genetics and Molecular Biology | 4 | 4% |
Nursing and Health Professions | 3 | 3% |
Environmental Science | 1 | 1% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 1% |
Other | 7 | 7% |
Unknown | 31 | 33% |