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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Total Synthesis, Structure, and Oral Absorption of a Thiazole Cyclic Peptide, Sanguinamide A
|
|---|---|
| Published in |
Organic Letters, November 2012
|
| DOI | 10.1021/ol3027347 |
| Pubmed ID | |
| Authors |
Daniel S. Nielsen, Huy N. Hoang, Rink-Jan Lohman, Frederik Diness, David P. Fairlie |
| Abstract |
The first total synthesis and three-dimensional solution structure are reported for sanguinamide A, a thiazole-containing cyclic peptide from the sea slug H. sanguineus. Solution phase fragment synthesis, solid phase fragment assembly, and solution macrocyclization were combined to give (1) in 10% yield. Spectral properties were identical for the natural product, requiring revision of its structure from (2) to (1). Intramolecular transannular hydrogen bonds help to bury polar atoms, which enables oral absorption from the gut. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 1% |
| United Kingdom | 1 | 1% |
| Germany | 1 | 1% |
| Unknown | 66 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 29% |
| Researcher | 18 | 26% |
| Student > Bachelor | 6 | 9% |
| Student > Doctoral Student | 5 | 7% |
| Professor > Associate Professor | 5 | 7% |
| Other | 7 | 10% |
| Unknown | 8 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 48 | 70% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Medicine and Dentistry | 3 | 4% |
| Social Sciences | 2 | 3% |
| Biochemistry, Genetics and Molecular Biology | 2 | 3% |
| Other | 1 | 1% |
| Unknown | 10 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 November 2012.
All research outputs
#15,256,044
of 22,685,926 outputs
Outputs from Organic Letters
#10,719
of 14,032 outputs
Outputs of similar age
#115,487
of 183,491 outputs
Outputs of similar age from Organic Letters
#116
of 159 outputs
Altmetric has tracked 22,685,926 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,032 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 183,491 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 159 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.