| Title |
The success of pharmacogenomics in moving genetic association studies from bench to bedside: study design and implementation of precision medicine in the post-GWAS era
|
|---|---|
| Published in |
Human Genetics, August 2012
|
| DOI | 10.1007/s00439-012-1221-z |
| Pubmed ID | |
| Authors |
Marylyn D. Ritchie |
| Abstract |
Pharmacogenomics is emerging as a popular type of study for human genetics in recent years. This is primarily due to the many success stories and high potential for translation to clinical practice. In this review, the strengths and limitations of pharmacogenomics are discussed as well as the primary epidemiologic, clinical trial, and in vitro study designs implemented. A brief discussion of molecular and analytic approaches will be reviewed. Finally, several examples of bench-to-bedside clinical implementations of pharmacogenetic traits will be described. Pharmacogenomics continues to grow in popularity because of the important genetic associations identified that drive the possibility of precision medicine. |
Mendeley readers
The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| France | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| United Kingdom | 1 | <1% |
| Italy | 1 | <1% |
| Nigeria | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 130 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 33 | 24% |
| Student > Master | 22 | 16% |
| Student > Ph. D. Student | 19 | 14% |
| Other | 10 | 7% |
| Professor | 8 | 6% |
| Other | 27 | 20% |
| Unknown | 19 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 34 | 25% |
| Medicine and Dentistry | 31 | 22% |
| Biochemistry, Genetics and Molecular Biology | 16 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 9% |
| Computer Science | 8 | 6% |
| Other | 15 | 11% |
| Unknown | 22 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2023.
All research outputs
#4,585,476
of 24,707,218 outputs
Outputs from Human Genetics
#431
of 3,067 outputs
Outputs of similar age
#30,805
of 175,574 outputs
Outputs of similar age from Human Genetics
#3
of 16 outputs
Altmetric has tracked 24,707,218 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,067 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one has done well, scoring higher than 85% of its peers.
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We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.