Title |
Expression Profiling of Archival Tumors for Long-term Health Studies
|
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Published in |
Clinical Cancer Research, November 2012
|
DOI | 10.1158/1078-0432.ccr-12-1915 |
Pubmed ID | |
Authors |
Levi Waldron, Shuji Ogino, Yujin Hoshida, Kaori Shima, Amy E. McCart Reed, Peter T. Simpson, Yoshifumi Baba, Katsuhiko Nosho, Nicola Segata, Ana Cristina Vargas, Margaret C. Cummings, Sunil R. Lakhani, Gregory J. Kirkner, Edward Giovannucci, John Quackenbush, Todd R. Golub, Charles S. Fuchs, Giovanni Parmigiani, Curtis Huttenhower |
Abstract |
More than 20 million archival tissue samples are stored annually in the United States as formalin-fixed, paraffin-embedded (FFPE) blocks, but RNA degradation during fixation and storage has prevented their use for transcriptional profiling. New and highly sensitive assays for whole-transcriptome microarray analysis of FFPE tissues are now available, but resulting data include noise and variability for which previous expression array methods are inadequate. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 7% |
Australia | 1 | 1% |
Canada | 1 | 1% |
United Kingdom | 1 | 1% |
Spain | 1 | 1% |
Denmark | 1 | 1% |
Unknown | 59 | 86% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 17 | 25% |
Researcher | 16 | 23% |
Professor > Associate Professor | 6 | 9% |
Student > Bachelor | 5 | 7% |
Other | 4 | 6% |
Other | 8 | 12% |
Unknown | 13 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 21 | 30% |
Medicine and Dentistry | 14 | 20% |
Biochemistry, Genetics and Molecular Biology | 12 | 17% |
Computer Science | 3 | 4% |
Business, Management and Accounting | 1 | 1% |
Other | 5 | 7% |
Unknown | 13 | 19% |