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Feasibility of focal transcranial DC polarization with simultaneous EEG recording: Preliminary assessment in healthy subjects and human epilepsy

Overview of attention for article published in Epilepsy & Behavior, November 2012
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Title
Feasibility of focal transcranial DC polarization with simultaneous EEG recording: Preliminary assessment in healthy subjects and human epilepsy
Published in
Epilepsy & Behavior, November 2012
DOI 10.1016/j.yebeh.2012.06.027
Pubmed ID
Authors

Paula Faria, Felipe Fregni, Fernando Sebastião, Ana I. Dias, Alberto Leal

Abstract

We aimed to investigate the feasibility of an experimental system for simultaneous transcranial DC stimulation (tDCS) and EEG recording in human epilepsy. We report tolerability of this system in a cross-over controlled trial with 15 healthy subjects and preliminary effects of its use, testing repeated tDCS sessions, in two patients with drug-refractory Continuous Spike-Wave Discharges During Slow Sleep (CSWS). Our system combining continuous recording of the EEG with tDCS allows detailed evaluation of the interictal activity during the entire process. Stimulation with 1 mA was well-tolerated in both healthy volunteers and patients with refractory epilepsy. The large reduction in interictal epileptiform EEG discharges in the two subjects with epilepsy supports further investigation of tDCS using this combined method of stimulation and monitoring in epilepsy. Continuous monitoring of epileptic activity throughout tDCS improves safety and allows detailed evaluation of epileptic activity changes induced by tDCS in patients.

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Mendeley readers

The data shown below were compiled from readership statistics for 126 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 2%
Italy 2 2%
Korea, Republic of 1 <1%
Spain 1 <1%
Germany 1 <1%
Unknown 118 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 31 25%
Student > Ph. D. Student 18 14%
Student > Master 14 11%
Student > Bachelor 13 10%
Other 9 7%
Other 25 20%
Unknown 16 13%
Readers by discipline Count As %
Medicine and Dentistry 31 25%
Neuroscience 24 19%
Psychology 17 13%
Engineering 11 9%
Agricultural and Biological Sciences 7 6%
Other 13 10%
Unknown 23 18%