| Title |
Low-pressure pulsed focused ultrasound with microbubbles promotes an anticancer immunological response
|
|---|---|
| Published in |
Journal of Translational Medicine, November 2012
|
| DOI | 10.1186/1479-5876-10-221 |
| Pubmed ID | |
| Authors |
Hao-Li Liu, Han-Yi Hsieh, Li-An Lu, Chiao-Wen Kang, Ming-Fang Wu, Chun-Yen Lin |
| Abstract |
High-intensity focused-ultrasound (HIFU) has been successfully employed for thermal ablation of tumors in clinical settings. Continuous- or pulsed-mode HIFU may also induce a host antitumor immune response, mainly through expansion of antigen-presenting cells in response to increased cellular debris and through increased macrophage activation/infiltration. Here we demonstrated that another form of focused ultrasound delivery, using low-pressure, pulsed-mode exposure in the presence of microbubbles (MBs), may also trigger an antitumor immunological response and inhibit tumor growth. |
Mendeley readers
The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| United Kingdom | 1 | <1% |
| Unknown | 102 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 32 | 30% |
| Researcher | 18 | 17% |
| Other | 10 | 10% |
| Student > Master | 9 | 9% |
| Student > Bachelor | 5 | 5% |
| Other | 14 | 13% |
| Unknown | 17 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 22% |
| Engineering | 18 | 17% |
| Agricultural and Biological Sciences | 9 | 9% |
| Biochemistry, Genetics and Molecular Biology | 7 | 7% |
| Physics and Astronomy | 5 | 5% |
| Other | 12 | 11% |
| Unknown | 31 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2020.
All research outputs
#7,419,285
of 22,685,926 outputs
Outputs from Journal of Translational Medicine
#1,228
of 3,962 outputs
Outputs of similar age
#58,052
of 180,076 outputs
Outputs of similar age from Journal of Translational Medicine
#19
of 56 outputs
Altmetric has tracked 22,685,926 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,962 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 180,076 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.