↓ Skip to main content

Clustering of time-course gene expression profiles using normal mixture models with autoregressive random effects

Overview of attention for article published in BMC Bioinformatics, November 2012
Altmetric Badge

Mentioned by

twitter
2 X users

Citations

dimensions_citation
24 Dimensions

Readers on

mendeley
50 Mendeley
citeulike
3 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Clustering of time-course gene expression profiles using normal mixture models with autoregressive random effects
Published in
BMC Bioinformatics, November 2012
DOI 10.1186/1471-2105-13-300
Pubmed ID
Authors

Kui Wang, Shu Kay Ng, Geoffrey J McLachlan

Abstract

Time-course gene expression data such as yeast cell cycle data may be periodically expressed. To cluster such data, currently used Fourier series approximations of periodic gene expressions have been found not to be sufficiently adequate to model the complexity of the time-course data, partly due to their ignoring the dependence between the expression measurements over time and the correlation among gene expression profiles. We further investigate the advantages and limitations of available models in the literature and propose a new mixture model with autoregressive random effects of the first order for the clustering of time-course gene-expression profiles. Some simulations and real examples are given to demonstrate the usefulness of the proposed models.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 2%
Brazil 1 2%
South Africa 1 2%
Russia 1 2%
Japan 1 2%
United States 1 2%
Unknown 44 88%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 28%
Researcher 13 26%
Professor > Associate Professor 7 14%
Student > Master 5 10%
Professor 2 4%
Other 7 14%
Unknown 2 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 40%
Computer Science 9 18%
Mathematics 6 12%
Biochemistry, Genetics and Molecular Biology 4 8%
Engineering 4 8%
Other 3 6%
Unknown 4 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2012.
All research outputs
#15,256,044
of 22,685,926 outputs
Outputs from BMC Bioinformatics
#5,361
of 7,253 outputs
Outputs of similar age
#112,615
of 179,003 outputs
Outputs of similar age from BMC Bioinformatics
#71
of 104 outputs
Altmetric has tracked 22,685,926 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,253 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 179,003 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 104 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.