| Title |
In vitroantimalarial susceptibility and molecular markers of drug resistance in Franceville, Gabon
|
|---|---|
| Published in |
BMC Infectious Diseases, November 2012
|
| DOI | 10.1186/1471-2334-12-307 |
| Pubmed ID | |
| Authors |
Rafika Zatra, Jean Bernard Lekana-douki, Faustin Lekoulou, Ulrick Bisvigou, Edgard Brice Ngoungou, Fousseyni S Toure Ndouo |
| Abstract |
Malaria remains a major public health problem, due largely to emergence and widespread P. falciparum drug resistance. WHO recommends artemisinine combination based therapy (ACT) to overcome P. falciparum drug resistance, but reports of declining ACT efficacy have been published. A thorough understanding of the molecular bases of P. falciparum resistance to existing drugs is therefore needed. The aims of this study were to analyze the in vitro sensitivity of P. falciparum field isolates from Franceville, Gabon, to chloroquine (CQ), mefloquine (MF), dihydroartemisinine (DHA) and monodesethylamodiaquine (MDAQ), and to investigate polymorphisms associated with drug resistance. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 4% |
| Tanzania, United Republic of | 1 | 2% |
| Unknown | 48 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 25% |
| Researcher | 7 | 14% |
| Student > Bachelor | 7 | 14% |
| Student > Master | 7 | 14% |
| Other | 3 | 6% |
| Other | 8 | 16% |
| Unknown | 6 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 12 | 24% |
| Medicine and Dentistry | 10 | 20% |
| Biochemistry, Genetics and Molecular Biology | 6 | 12% |
| Computer Science | 5 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 6% |
| Other | 8 | 16% |
| Unknown | 7 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 November 2012.
All research outputs
#20,172,971
of 22,685,926 outputs
Outputs from BMC Infectious Diseases
#6,425
of 7,643 outputs
Outputs of similar age
#158,752
of 178,791 outputs
Outputs of similar age from BMC Infectious Diseases
#119
of 152 outputs
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