| Title |
How Many Contralateral Carcinomas in Patients with Unilateral Papillary Thyroid Microcarcinoma are Preoperatively Misdiagnosed as Benign?
|
|---|---|
| Published in |
World Journal of Surgery, August 2016
|
| DOI | 10.1007/s00268-016-3701-0 |
| Pubmed ID | |
| Authors |
Zeng Gui Wu, Xing Qiang Yan, Ru Si Su, Zhao Sheng Ma, Bo Jian Xie, Fei Lin Cao |
| Abstract |
The decision to perform a total thyroidectomy (TT) for unilateral papillary thyroid microcarcinoma (PTMC) with nodules in the contralateral lobe remains controversial. The aim of this study was to investigate the rate of contralateral carcinomas that are preoperatively misdiagnosed as benign. From October 2011 to October 2015, a total of 347 patients with unilateral PTMC and contralateral benign nodules who were treated with a TT at a single institution were enrolled. All patients underwent preoperative fine needle aspiration and ultrasonography (US). Clinicopathological features such as age, sex, laterality, tumor size, central lymph node metastases, capsular invasion, TgAb and TPOAb levels, Hashimoto's thyroiditis, nodule number in both lobes according to preoperative US, and primary carcinoma number in the final postoperative pathology report were all analyzed to investigate the rate and predictive factors of contralateral carcinoma. A total of 100 patients (28.9 %) were diagnosed with papillary thyroid carcinoma in the contralateral lobe. A multivariate analysis showed that tumor size, nodule number in the contralateral lobe, and multifocality of the primary tumor were all independent predictive factors of contralateral carcinoma in patients with unilateral PTMC and contralateral benign nodules. According to our findings, the rate at which contralateral carcinomas are preoperatively misdiagnosed as benign is 28.9 %. A TT is essential for unilateral PTMC with a primary tumor size >5 mm, multifocal primary carcinomas or multifocal benign nodules in the contralateral lobe. |
X Demographics
The data shown below were collected from the profiles of 19 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 26% |
| Poland | 1 | 5% |
| Spain | 1 | 5% |
| Saudi Arabia | 1 | 5% |
| Unknown | 11 | 58% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 47% |
| Practitioners (doctors, other healthcare professionals) | 6 | 32% |
| Scientists | 3 | 16% |
| Science communicators (journalists, bloggers, editors) | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 22 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Unspecified | 3 | 14% |
| Student > Doctoral Student | 3 | 14% |
| Other | 2 | 9% |
| Professor | 2 | 9% |
| Professor > Associate Professor | 2 | 9% |
| Other | 5 | 23% |
| Unknown | 5 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 10 | 45% |
| Unspecified | 3 | 14% |
| Psychology | 2 | 9% |
| Agricultural and Biological Sciences | 1 | 5% |
| Unknown | 6 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 February 2017.
All research outputs
#3,193,075
of 24,592,508 outputs
Outputs from World Journal of Surgery
#449
of 4,495 outputs
Outputs of similar age
#53,961
of 350,570 outputs
Outputs of similar age from World Journal of Surgery
#17
of 72 outputs
Altmetric has tracked 24,592,508 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,495 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done well, scoring higher than 89% of its peers.
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We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.