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Is There Potential for Repurposing Statins as Novel Antimicrobials?

Overview of attention for article published in Antimicrobial Agents and Chemotherapy, August 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

news
1 news outlet
twitter
13 X users
patent
4 patents

Citations

dimensions_citation
90 Dimensions

Readers on

mendeley
113 Mendeley
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Title
Is There Potential for Repurposing Statins as Novel Antimicrobials?
Published in
Antimicrobial Agents and Chemotherapy, August 2016
DOI 10.1128/aac.00192-16
Pubmed ID
Authors

Emma Hennessy, Claire Adams, F. Jerry Reen, Fergal O'Gara

Abstract

Statins are a class of pharmaceutical widely used to treat high serum cholesterol. In addition, statins have so-called "pleiotropic effects", which include the reduction of inflammation, immunomodulation, and anti-microbial effects. An increasing number of studies are emerging which detail the attenuation of bacterial growth and in vitro and in vivo virulence by statin treatment. In this review, we describe the current information available surrounding the effects of statins on bacterial infections, and provide insight regarding the potential use of these compounds as anti-microbial therapeutic agents.

X Demographics

X Demographics

The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 113 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 113 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 12%
Student > Master 13 12%
Student > Bachelor 13 12%
Student > Ph. D. Student 12 11%
Other 6 5%
Other 25 22%
Unknown 30 27%
Readers by discipline Count As %
Medicine and Dentistry 24 21%
Biochemistry, Genetics and Molecular Biology 14 12%
Pharmacology, Toxicology and Pharmaceutical Science 12 11%
Immunology and Microbiology 10 9%
Agricultural and Biological Sciences 6 5%
Other 8 7%
Unknown 39 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 February 2023.
All research outputs
#1,678,926
of 25,728,855 outputs
Outputs from Antimicrobial Agents and Chemotherapy
#610
of 15,641 outputs
Outputs of similar age
#29,513
of 356,395 outputs
Outputs of similar age from Antimicrobial Agents and Chemotherapy
#27
of 270 outputs
Altmetric has tracked 25,728,855 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 15,641 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 356,395 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 270 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.