Title |
The effect of aerobic exercise on cortical architecture in patients with chronic schizophrenia: a randomized controlled MRI study
|
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Published in |
European Archives of Psychiatry and Clinical Neuroscience, November 2012
|
DOI | 10.1007/s00406-012-0383-y |
Pubmed ID | |
Authors |
Peter Falkai, Berend Malchow, Thomas Wobrock, Oliver Gruber, Andrea Schmitt, William G. Honer, Frank-Gerald Pajonk, Frank Sun, Tyrone D. Cannon |
Abstract |
Via influencing brain plasticity, aerobic exercise could contribute to the treatment of schizophrenia patients. As previously shown, physical exercise increases hippocampus volume and improves short-term memory. We now investigated gray matter density and brain surface expansion in this sample using MRI-based cortical pattern matching methods. Comparing schizophrenia patients to healthy controls before and after 3 months of aerobic exercise training (cycling) plus patients playing table football yielded gray matter density increases in the right frontal and occipital cortex merely in healthy controls. However, respective exercise effects might be attenuated in chronic schizophrenia, which should be verified in a larger sample. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Portugal | 1 | <1% |
Netherlands | 1 | <1% |
Spain | 1 | <1% |
Japan | 1 | <1% |
United States | 1 | <1% |
Unknown | 152 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 29 | 18% |
Student > Ph. D. Student | 21 | 13% |
Student > Bachelor | 18 | 11% |
Student > Doctoral Student | 17 | 11% |
Researcher | 12 | 8% |
Other | 26 | 17% |
Unknown | 34 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 28 | 18% |
Psychology | 26 | 17% |
Sports and Recreations | 15 | 10% |
Neuroscience | 13 | 8% |
Nursing and Health Professions | 8 | 5% |
Other | 23 | 15% |
Unknown | 44 | 28% |