Title |
Nomenclature of homodetic cyclic peptides produced from ribosomal precursors: An IUPAC task group interim report
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Published in |
Biospectroscopy, November 2016
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DOI | 10.1002/bip.22939 |
Pubmed ID | |
Authors |
David J. Craik, Youn Young Shim, Ulf Göransson, Gerard P. Moss, Ninghua Tan, Pramodkumar D. Jadhav, Jianheng Shen, Martin J. T. Reaney |
Abstract |
In 2015, an International Union of Pure and Applied Chemistry (IUPAC) Task Group was formed to develop nomenclature recommendations for homodetic cyclic peptides produced from ribosomal precursors. Delegates of the 2015 International Conference on Circular Proteins (ICCP) were presented with the strengths and weaknesses of four published approaches to homodetic cyclic peptide nomenclature, and a summary of the ensuing discussion is presented here. This interim report presents a potentially novel suggestion - the use of Cahn-Ingold-Prelog rules to specify amino acid priority in homodetic peptides for consistent numbering. Indeed, this might be the first extension of the Cahn-Ingold-Prelog rules in five decades. The authors invite interested parties to contact the corresponding author with suggestions for the improvement of the proposed nomenclature; these ideas will be discussed and considered for inclusion in the final report. This article is protected by copyright. All rights reserved. |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 4 | 29% |
Researcher | 4 | 29% |
Student > Bachelor | 1 | 7% |
Student > Doctoral Student | 1 | 7% |
Unknown | 4 | 29% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 3 | 21% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 14% |
Agricultural and Biological Sciences | 2 | 14% |
Chemistry | 2 | 14% |
Unknown | 5 | 36% |