Title |
Fibroblast growth factor receptor 1 (FGFR1) variants and craniofacial variation in Amerindians and related populations
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Published in |
American Journal of Human Biology, October 2012
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DOI | 10.1002/ajhb.22331 |
Pubmed ID | |
Authors |
Jorge A. Gómez‐Valdés, Tábita Hünemeier, Verônica Contini, Victor Acuña‐Alonzo, Gastón Macin, Mónica Ballesteros‐Romero, Pau Corral, Andres Ruiz‐Linares, Gabriela Sánchez‐Mejorada, Samuel Canizales‐Quinteros, Neus Martínez‐Abadías, Francisco M. Salzano, Rolando González‐José, Maria cátira Bortolini |
Abstract |
The polymorphic site rs4647905 of the FGFR1 gene was previously associated with a decrease in cephalic index (CI). Here, we evaluate the relationships between genotypes and cephalometric measurements and indices in one Mexican Native and two mestizo Mexican populations using two haplotype-tag SNPs (rs4647905 and rs3213849) that represent >85% of the FGFR1 variability, plus three other SNPs (rs2293971, rs2304000, and rs930828) situated nearby. In addition, we genotyped five South American natives, two European, one African, and one Siberian populations to evaluate their intra and intercontinental population diversity. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | 2% |
Argentina | 1 | 2% |
Unknown | 39 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 20% |
Student > Bachelor | 8 | 20% |
Student > Master | 6 | 15% |
Researcher | 5 | 12% |
Student > Postgraduate | 3 | 7% |
Other | 7 | 17% |
Unknown | 4 | 10% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 12 | 29% |
Medicine and Dentistry | 8 | 20% |
Biochemistry, Genetics and Molecular Biology | 5 | 12% |
Arts and Humanities | 2 | 5% |
Computer Science | 2 | 5% |
Other | 5 | 12% |
Unknown | 7 | 17% |