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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Mesenchymal stem cells for systemic therapy: Shotgun approach or magic bullets?
|
|---|---|
| Published in |
BioEssays, November 2012
|
| DOI | 10.1002/bies.201200087 |
| Pubmed ID | |
| Authors |
Susan M. Millard, Nicholas M. Fisk |
| Abstract |
Given their heterogeneity and lack of defining markers, it is surprising that multipotent mesenchymal stem/stromal cells (MSCs) have attracted so much translational attention, especially as increasing evidence points to their predominant effect being not by donor differentiation but via paracrine mediators and exosomes. Achieving long-term MSC donor chimerism for treatment of chronic disease remains a challenge, requiring enhanced MSC homing/engraftment properties and manipulation of niches to direct MSC behaviour. Meanwhile advances in nanoparticle technology are furthering the development of MSCs as vehicles for targeted drug delivery. For treatment of acute injuries, systemic cell-free exosome delivery may ultimately displace current emphasis on empiric donor-cell transplantation for anti-inflammatory, immunomodulatory and repair-promoting effects. Exploration of potential clinical sources of MSCs has led to increased utilisation of perinatal MSCs in allogeneic clinical trials, reflecting their ease of collection and developmentally advantageous properties. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 1% |
| United Kingdom | 1 | 1% |
| Singapore | 1 | 1% |
| Denmark | 1 | 1% |
| Spain | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 82 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 22% |
| Researcher | 18 | 20% |
| Student > Bachelor | 11 | 13% |
| Student > Master | 9 | 10% |
| Professor > Associate Professor | 6 | 7% |
| Other | 20 | 23% |
| Unknown | 5 | 6% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 27 | 31% |
| Medicine and Dentistry | 20 | 23% |
| Biochemistry, Genetics and Molecular Biology | 11 | 13% |
| Engineering | 5 | 6% |
| Psychology | 4 | 5% |
| Other | 11 | 13% |
| Unknown | 10 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2014.
All research outputs
#7,593,701
of 24,417,958 outputs
Outputs from BioEssays
#1,213
of 2,967 outputs
Outputs of similar age
#77,069
of 285,776 outputs
Outputs of similar age from BioEssays
#10
of 33 outputs
Altmetric has tracked 24,417,958 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 2,967 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.8. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 285,776 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.