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Single-use disposable technologies for biopharmaceutical manufacturing

Overview of attention for article published in Trends in Biotechnology, November 2012
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
3 news outlets
twitter
2 X users
patent
15 patents
googleplus
1 Google+ user

Citations

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199 Dimensions

Readers on

mendeley
609 Mendeley
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Title
Single-use disposable technologies for biopharmaceutical manufacturing
Published in
Trends in Biotechnology, November 2012
DOI 10.1016/j.tibtech.2012.10.004
Pubmed ID
Authors

Abhinav A. Shukla, Uwe Gottschalk

Abstract

The manufacture of protein biopharmaceuticals is conducted under current good manufacturing practice (cGMP) and involves multiple unit operations for upstream production and downstream purification. Until recently, production facilities relied on the use of relatively inflexible, hard-piped equipment including large stainless steel bioreactors and tanks to hold product intermediates and buffers. However, there is an increasing trend towards the adoption of single-use technologies across the manufacturing process. Technical advances have now made an end-to-end single-use manufacturing facility possible, but several aspects of single-use technology require further improvement and are continually evolving. This article provides a perspective on the current state-of-the-art in single-use technologies and highlights trends that will improve performance and increase the market penetration of disposable manufacturing in the future.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 609 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 3 <1%
United States 2 <1%
Switzerland 1 <1%
France 1 <1%
Brazil 1 <1%
India 1 <1%
Malaysia 1 <1%
Mexico 1 <1%
Canada 1 <1%
Other 2 <1%
Unknown 595 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 130 21%
Student > Bachelor 124 20%
Student > Ph. D. Student 86 14%
Researcher 56 9%
Other 25 4%
Other 55 9%
Unknown 133 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 100 16%
Engineering 95 16%
Biochemistry, Genetics and Molecular Biology 92 15%
Chemical Engineering 66 11%
Pharmacology, Toxicology and Pharmaceutical Science 35 6%
Other 70 11%
Unknown 151 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 33. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2024.
All research outputs
#1,206,112
of 25,374,917 outputs
Outputs from Trends in Biotechnology
#123
of 2,856 outputs
Outputs of similar age
#9,466
of 285,367 outputs
Outputs of similar age from Trends in Biotechnology
#1
of 28 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,856 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.5. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 285,367 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.