| Title |
Clozapine and therapeutic drug monitoring: is there sufficient evidence for an upper threshold?
|
|---|---|
| Published in |
Psychopharmacology, November 2012
|
| DOI | 10.1007/s00213-012-2922-7 |
| Pubmed ID | |
| Authors |
Gary Remington, Ofer Agid, George Foussias, Larissa Ferguson, Krysta McDonald, Valerie Powell |
| Abstract |
Clozapine levels are advocated in the monitoring of patients on this drug and have now been used for a number of years. A safety-related threshold has also been proposed, as well as therapeutic lower and upper thresholds. While there has been reasonable consensus regarding a lower therapeutic threshold, this is not the case for the upper thresholds. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 134 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 4 | 3% |
| Switzerland | 1 | <1% |
| Chile | 1 | <1% |
| Italy | 1 | <1% |
| India | 1 | <1% |
| United Kingdom | 1 | <1% |
| Denmark | 1 | <1% |
| Unknown | 124 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 16 | 12% |
| Student > Master | 16 | 12% |
| Student > Ph. D. Student | 14 | 10% |
| Other | 11 | 8% |
| Student > Bachelor | 10 | 7% |
| Other | 36 | 27% |
| Unknown | 31 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 59 | 44% |
| Nursing and Health Professions | 6 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 4% |
| Agricultural and Biological Sciences | 4 | 3% |
| Psychology | 4 | 3% |
| Other | 15 | 11% |
| Unknown | 40 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 December 2012.
All research outputs
#17,485,371
of 25,708,267 outputs
Outputs from Psychopharmacology
#4,229
of 5,353 outputs
Outputs of similar age
#192,446
of 286,665 outputs
Outputs of similar age from Psychopharmacology
#21
of 35 outputs
Altmetric has tracked 25,708,267 research outputs across all sources so far. This one is in the 31st percentile – i.e., 31% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,353 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.1. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 286,665 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.