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Long-term Treatment of Teicoplanin for Methicillin-resistant Staphylococcus aureus Sternal Osteomyelitis with Renal Impairment: A Case of High Teicoplanin Trough Levels Maintained by Therapeutic Drug…

Overview of attention for article published in Yakugaku Zasshi = Journal of Pharmaceutical Society of Japan, September 2016
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Title
Long-term Treatment of Teicoplanin for Methicillin-resistant Staphylococcus aureus Sternal Osteomyelitis with Renal Impairment: A Case of High Teicoplanin Trough Levels Maintained by Therapeutic Drug Monitoring
Published in
Yakugaku Zasshi = Journal of Pharmaceutical Society of Japan, September 2016
DOI 10.1248/yakushi.15-00296
Pubmed ID
Authors

潮平 英郎, 仲松 正司, 喜瀬 勇也, 比嘉 太, 健山 正男, 外間 惟夫, 国吉 幸男, 植田 真一郎, 中村 克徳, 藤田 次郎

Abstract

Teicoplanin, a glycopeptide antibiotic for methicillin-resistant Staphylococcus aureus, is recommended for therapeutic drug monitoring during treatment. Maintaining a high trough range of teicoplanin is also recommended for severe infectious disease. However, the optimal dose and interval of treatment for severe renal impairment is unknown. We report a 79-year-old man who received long-term teicoplanin treatment for methicillin-resistant Staphylococcus aureus bacteremia due to postoperative sternal osteomyelitis with renal impairment. Plasma teicoplanin trough levels were maintained at a high range (20-30 μg/mL). Although the patient required long-term teicoplanin treatment, a further decline in renal function was not observed, and blood culture remained negative after the start of treatment. Teicoplanin treatment that is maintained at a high trough level by therapeutic drug monitoring might be beneficial for severe methicillin-resistant Staphylococcus aureus infection accompanied by renal impairment.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 26%
Other 3 16%
Student > Postgraduate 2 11%
Student > Ph. D. Student 1 5%
Researcher 1 5%
Other 1 5%
Unknown 6 32%
Readers by discipline Count As %
Medicine and Dentistry 6 32%
Pharmacology, Toxicology and Pharmaceutical Science 3 16%
Biochemistry, Genetics and Molecular Biology 1 5%
Psychology 1 5%
Agricultural and Biological Sciences 1 5%
Other 0 0%
Unknown 7 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 May 2017.
All research outputs
#19,944,091
of 25,373,627 outputs
Outputs from Yakugaku Zasshi = Journal of Pharmaceutical Society of Japan
#1,581
of 1,958 outputs
Outputs of similar age
#257,778
of 348,369 outputs
Outputs of similar age from Yakugaku Zasshi = Journal of Pharmaceutical Society of Japan
#3
of 6 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,958 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 348,369 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.