Title |
BRAF V600E Mutation Analysis in Papillary Thyroid Carcinomas by Peptide Nucleic Acid Clamp Real-time PCR
|
---|---|
Published in |
Annals of Surgical Oncology, November 2012
|
DOI | 10.1245/s10434-012-2494-0 |
Pubmed ID | |
Authors |
Dongjun Jeong, Yujun Jeong, Ji Hye Park, Sun Wook Han, Sung Yong Kim, Yeo Joo Kim, Sang Jin Kim, Young Hwangbo, Soyoung Park, Hyun Deuk Cho, Mee Hye Oh, Seung Ha Yang, Chang Jin Kim |
Abstract |
Activating somatic mutation of the BRAF (V600E) has been identified as the most common genetic event in papillary thyroid carcinoma (PTC) with a variable frequency (32-87%) in different series by different methods. The BRAF (V600E) mutation is associated with various clinicopathological parameters. The mutation is an important factor for the management of the PTC patients. The objective of this study was to detect the BRAF (V600E) mutation in PTCs by peptide nucleic acid (PNA) clamp real-time PCR and to analyze the results with clinicopathological parameters. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Korea, Republic of | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 3 | 17% |
Professor | 3 | 17% |
Researcher | 2 | 11% |
Lecturer | 1 | 6% |
Other | 1 | 6% |
Other | 4 | 22% |
Unknown | 4 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 44% |
Agricultural and Biological Sciences | 2 | 11% |
Biochemistry, Genetics and Molecular Biology | 2 | 11% |
Psychology | 1 | 6% |
Engineering | 1 | 6% |
Other | 0 | 0% |
Unknown | 4 | 22% |