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Vironome of Kaposi sarcoma associated herpesvirus-inflammatory cytokine syndrome in an AIDS patient reveals co-infection of human herpesvirus 8 and human herpesvirus 6A

Overview of attention for article published in Virology, August 2012
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  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

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3 X users
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1 Wikipedia page

Citations

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37 Dimensions

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44 Mendeley
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Title
Vironome of Kaposi sarcoma associated herpesvirus-inflammatory cytokine syndrome in an AIDS patient reveals co-infection of human herpesvirus 8 and human herpesvirus 6A
Published in
Virology, August 2012
DOI 10.1016/j.virol.2012.08.014
Pubmed ID
Authors

Kristen M. Tamburro, Dongmei Yang, Jessica Poisson, Yuri Fedoriw, Debasmita Roy, Amy Lucas, Sang-Hoon Sin, Nadia Malouf, Vincent Moylan, Blossom Damania, Stephan Moll, Charles van der Horst, Dirk P. Dittmer

Abstract

KSHV inflammatory cytokine syndrome (KICS) is a newly described condition characterized by systemic illness as a result of systemic, lytic KSHV infection. We used Illumina sequencing to establish the DNA vironome of blood from such a patient. It identified concurrent high-level viremia of human herpesvirus (HHV) 8 and 6a. The HHV8 plasma viral load was 5,300,000 copies/ml, which is the highest reported to date; this despite less than five skin lesions and no HHV8 associated lymphoma. This is the first report of systemic HHV6a/KSHV co-infection in a patient. It is the first whole genome KSHV sequence to be determined directly from patient plasma rather than cultured or biopsied tumor material. This case supports KICS as a new clinical entity associated with KSHV.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 5%
France 1 2%
Unknown 41 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 20%
Student > Ph. D. Student 8 18%
Student > Postgraduate 5 11%
Student > Master 4 9%
Professor 3 7%
Other 7 16%
Unknown 8 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 39%
Medicine and Dentistry 12 27%
Biochemistry, Genetics and Molecular Biology 4 9%
Immunology and Microbiology 1 2%
Veterinary Science and Veterinary Medicine 1 2%
Other 0 0%
Unknown 9 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 February 2013.
All research outputs
#6,876,021
of 25,374,917 outputs
Outputs from Virology
#3,207
of 9,498 outputs
Outputs of similar age
#49,776
of 186,744 outputs
Outputs of similar age from Virology
#14
of 51 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 9,498 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 186,744 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.