| Title |
Quantitative mass spectrometry in proteomics: critical review update from 2007 to the present
|
|---|---|
| Published in |
Analytical & Bioanalytical Chemistry, July 2012
|
| DOI | 10.1007/s00216-012-6203-4 |
| Pubmed ID | |
| Authors |
Marcus Bantscheff, Simone Lemeer, Mikhail M. Savitski, Bernhard Kuster |
| Abstract |
Mass-spectrometry-based proteomics is continuing to make major contributions to the discovery of fundamental biological processes and, more recently, has also developed into an assay platform capable of measuring hundreds to thousands of proteins in any biological system. The field has progressed at an amazing rate over the past five years in terms of technology as well as the breadth and depth of applications in all areas of the life sciences. Some of the technical approaches that were at an experimental stage back then are considered the gold standard today, and the community is learning to come to grips with the volume and complexity of the data generated. The revolution in DNA/RNA sequencing technology extends the reach of proteomic research to practically any species, and the notion that mass spectrometry has the potential to eventually retire the western blot is no longer in the realm of science fiction. In this review, we focus on the major technical and conceptual developments since 2007 and illustrate these by important recent applications. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 1,036 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 12 | 1% |
| United Kingdom | 8 | <1% |
| Germany | 6 | <1% |
| Netherlands | 3 | <1% |
| Norway | 2 | <1% |
| Mexico | 2 | <1% |
| Sweden | 2 | <1% |
| France | 1 | <1% |
| South Africa | 1 | <1% |
| Other | 12 | 1% |
| Unknown | 987 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 302 | 29% |
| Researcher | 180 | 17% |
| Student > Master | 155 | 15% |
| Student > Bachelor | 97 | 9% |
| Student > Doctoral Student | 53 | 5% |
| Other | 103 | 10% |
| Unknown | 146 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 317 | 31% |
| Biochemistry, Genetics and Molecular Biology | 255 | 25% |
| Chemistry | 122 | 12% |
| Medicine and Dentistry | 40 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 20 | 2% |
| Other | 110 | 11% |
| Unknown | 172 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2024.
All research outputs
#2,082,036
of 25,374,917 outputs
Outputs from Analytical & Bioanalytical Chemistry
#126
of 9,619 outputs
Outputs of similar age
#12,413
of 177,935 outputs
Outputs of similar age from Analytical & Bioanalytical Chemistry
#1
of 66 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,619 research outputs from this source. They receive a mean Attention Score of 3.1. This one has done particularly well, scoring higher than 98% of its peers.
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We're also able to compare this research output to 66 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.