Title |
Pathology and Pathogenesis of Fatal Bordetella pertussis Infection in Infants
|
---|---|
Published in |
Clinical Infectious Diseases, August 2008
|
DOI | 10.1086/589753 |
Pubmed ID | |
Authors |
Christopher D. Paddock, Gary N. Sanden, James D. Cherry, Anthony A. Gal, Claire Langston, Kathleen M. Tatti, Kai-Hui Wu, Cynthia S. Goldsmith, Patricia W. Greer, Jeltley L. Montague, Mark T. Eliason, Robert C. Holman, Jeannette Guarner, Wun-Ju Shieh, Sherif R. Zaki |
Abstract |
Each year, Bordetella pertussis infection causes an estimated 294,000 deaths worldwide, primarily among young, nonvaccinated children. Approximately 90% of all deaths due to pertussis in the Unites States occur in young infants. These children often develop intractable pulmonary hypertension; however, the pathophysiologic mechanism responsible for this complication has not been well characterized, and there have been no detailed descriptions of the pathology of this disease since the 1940s. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 40% |
Unknown | 3 | 60% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 80% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 2 | <1% |
United Kingdom | 1 | <1% |
Brazil | 1 | <1% |
Slovakia | 1 | <1% |
Philippines | 1 | <1% |
Unknown | 210 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 33 | 15% |
Student > Ph. D. Student | 32 | 15% |
Researcher | 32 | 15% |
Student > Master | 21 | 10% |
Other | 17 | 8% |
Other | 47 | 22% |
Unknown | 34 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 76 | 35% |
Agricultural and Biological Sciences | 38 | 18% |
Biochemistry, Genetics and Molecular Biology | 25 | 12% |
Immunology and Microbiology | 16 | 7% |
Nursing and Health Professions | 5 | 2% |
Other | 22 | 10% |
Unknown | 34 | 16% |