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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Synthesis of bivalent glycoclusters containing GlcNAc as hexasaccharide mimetics. Bactericidal activity against Helicobacter pylori
|
|---|---|
| Published in |
Carbohydrate Research, July 2012
|
| DOI | 10.1016/j.carres.2012.07.011 |
| Pubmed ID | |
| Authors |
Dandan Yan, Julie Naughton, Marguerite Clyne, Paul V. Murphy |
| Abstract |
The Cu(I) catalysed cycloaddition reaction of azides and alkynes has been used to generate a series of divalent GlcNAc clusters with both α and β configurations. These glycoclusters can be considered as potential mimetics of an anti Helicobacter pylori hexasaccharide as they present two GlcNAc residues grafted onto a core scaffold. Two bivalent compounds based on α-O-GlcNAc were identified that selectively reduced the viability of H. pylori. These compounds showed activity towards different strains of H. pylori (Pu4 vs P12). The activity of the oligosaccharide mimetics is speculated to be due to the GlcNAc residues being able to adopt spatial arrangements accessible to the anti H. pylori hexasaccharide which may be important for activity. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Ireland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 19 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 21% |
| Researcher | 4 | 21% |
| Student > Bachelor | 3 | 16% |
| Student > Doctoral Student | 2 | 11% |
| Student > Postgraduate | 2 | 11% |
| Other | 3 | 16% |
| Unknown | 1 | 5% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 5 | 26% |
| Agricultural and Biological Sciences | 3 | 16% |
| Biochemistry, Genetics and Molecular Biology | 2 | 11% |
| Computer Science | 2 | 11% |
| Business, Management and Accounting | 1 | 5% |
| Other | 4 | 21% |
| Unknown | 2 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 December 2012.
All research outputs
#17,302,400
of 25,394,764 outputs
Outputs from Carbohydrate Research
#4,082
of 5,022 outputs
Outputs of similar age
#117,968
of 179,112 outputs
Outputs of similar age from Carbohydrate Research
#14
of 18 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,022 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 179,112 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.