Title |
Comparison of Central Venous Catheter and Peripheral Vein Samples of Antibiotics in Children With Cystic Fibrosis
|
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Published in |
Journal for Specialists in Pediatric Nursing, November 2012
|
DOI | 10.1111/jspn.12006 |
Pubmed ID | |
Authors |
Karen Wilson, Patricia A. Jamerson |
Abstract |
PURPOSE.: To determine if accurate serum antibiotic levels can be obtained from central venous catheters (CVCs) in pediatric patients with cystic fibrosis. DESIGN AND METHODS.: Fifty paired CVC-peripheral vancomycin or tobramycin specimens were collected within 5 min of each other following a 5-ml flush and discard. Specimen samples were randomized by first site drawn. RESULTS.: CVC-peripheral antibiotic levels were highly correlated (r =.97, p <.001), with no statistically significant difference (t = 1.18, p =.25). Bland-Altman plot analysis revealed a bias of.47, with limits of agreement ranging from -4.20 to 6.87. PRACTICE IMPLICATIONS.: Accurate antibiotic concentrations can be obtained from CVCs, reducing pediatric patient trauma and stress. |
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Demographic breakdown
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Mendeley readers
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Student > Bachelor | 5 | 15% |
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