| Title |
Prolonged administration of recombinant human erythropoietin increases submaximal performance more than maximal aerobic capacity
|
|---|---|
| Published in |
European Journal of Applied Physiology, August 2007
|
| DOI | 10.1007/s00421-007-0522-8 |
| Pubmed ID | |
| Authors |
J. J. Thomsen, R. L. Rentsch, P. Robach, J. A. L. Calbet, R. Boushel, P. Rasmussen, C. Juel, C. Lundby |
| Abstract |
The effects of recombinant human erythropoietin (rHuEpo) treatment on aerobic power (VO2max) are well documented, but little is known about the effects of rHuEpo on submaximal exercise performance. The present study investigated the effect on performance (ergometer cycling, 20-30 min at 80% of maximal attainable workload), and for this purpose eight subjects received either 5,000 IU rHuEpo or placebo every second day for 14 days, and subsequently a single dose of 5,000 IU/placebo weekly/10 weeks. Exercise performance was evaluated before treatment and after 4 and 11 weeks of treatment. With rHuEpo treatment VO2max increased (P<0.05) by 12.6 and 11.6% in week 4 and 11, respectively, and time-to-exhaustion (80% VO2max) was increased by 54.0 and 54.3% (P<0.05) after 4 and 11 weeks of treatment, respectively. However, when normalizing the workload to the same relative intensity (only done at time point week 11), TTE was decreased by 26.8% as compared to pre rHuEpo administration. In conclusion, in healthy non-athlete subjects rHuEpo administration prolongs submaximal exercise performance by about 54% independently of the approximately 12% increase in VO2max. |
X Demographics
The data shown below were collected from the profiles of 19 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 3 | 16% |
| United Kingdom | 3 | 16% |
| United States | 2 | 11% |
| Venezuela, Bolivarian Republic of | 1 | 5% |
| Norway | 1 | 5% |
| Slovakia | 1 | 5% |
| Unknown | 8 | 42% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 13 | 68% |
| Scientists | 4 | 21% |
| Science communicators (journalists, bloggers, editors) | 2 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 164 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 5 | 3% |
| United States | 2 | 1% |
| Canada | 2 | 1% |
| Germany | 1 | <1% |
| Switzerland | 1 | <1% |
| Spain | 1 | <1% |
| Denmark | 1 | <1% |
| Unknown | 151 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 40 | 24% |
| Student > Master | 24 | 15% |
| Student > Ph. D. Student | 20 | 12% |
| Researcher | 13 | 8% |
| Professor | 7 | 4% |
| Other | 29 | 18% |
| Unknown | 31 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Sports and Recreations | 46 | 28% |
| Medicine and Dentistry | 26 | 16% |
| Agricultural and Biological Sciences | 24 | 15% |
| Biochemistry, Genetics and Molecular Biology | 12 | 7% |
| Nursing and Health Professions | 8 | 5% |
| Other | 15 | 9% |
| Unknown | 33 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2022.
All research outputs
#1,534,172
of 25,374,647 outputs
Outputs from European Journal of Applied Physiology
#488
of 4,345 outputs
Outputs of similar age
#2,741
of 76,008 outputs
Outputs of similar age from European Journal of Applied Physiology
#5
of 29 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,345 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 76,008 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.