| Title |
Human tumor-derived vs dendritic cell-derived exosomes have distinct biologic roles and molecular profiles
|
|---|---|
| Published in |
Immunologic Research, January 2006
|
| DOI | 10.1385/ir:36:1:247 |
| Pubmed ID | |
| Authors |
Eva Wieckowski, Theresa L. Whiteside |
| Abstract |
Microvesicles (MV) or exosomes are produced and secreted by tumor and normal cells. The molecular profile and functions of tumor-derived vs dendritic cell (DC)-derived MV are distinct. The former express death ligands and mediate apoptosis of activated T cells. The latter promote CD4+ T cell proliferation and may play a role in regulating T cell responses. Serving as intercellular communication networks, tumor-derived MV contribute to tumor escape, while DC-derived MV drive and regulate immune response. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 1 | 1% |
| Argentina | 1 | 1% |
| Unknown | 80 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 20 | 24% |
| Student > Ph. D. Student | 14 | 17% |
| Student > Master | 10 | 12% |
| Student > Bachelor | 7 | 9% |
| Other | 7 | 9% |
| Other | 17 | 21% |
| Unknown | 7 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 30% |
| Medicine and Dentistry | 22 | 27% |
| Biochemistry, Genetics and Molecular Biology | 11 | 13% |
| Immunology and Microbiology | 6 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Other | 8 | 10% |
| Unknown | 8 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 August 2023.
All research outputs
#3,710,309
of 25,374,647 outputs
Outputs from Immunologic Research
#106
of 948 outputs
Outputs of similar age
#12,641
of 174,005 outputs
Outputs of similar age from Immunologic Research
#1
of 22 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 948 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 174,005 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.