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Is there a maximal anabolic response to protein intake with a meal?

Overview of attention for article published in Clinical Nutrition, December 2012
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

news
1 news outlet
twitter
193 X users
facebook
38 Facebook pages
googleplus
2 Google+ users
reddit
2 Redditors
pinterest
1 Pinner
video
10 YouTube creators

Citations

dimensions_citation
126 Dimensions

Readers on

mendeley
277 Mendeley
citeulike
2 CiteULike
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Title
Is there a maximal anabolic response to protein intake with a meal?
Published in
Clinical Nutrition, December 2012
DOI 10.1016/j.clnu.2012.11.018
Pubmed ID
Authors

Nicolaas E. Deutz, Robert R. Wolfe

Abstract

Several recent publications indicate that the maximum stimulation of muscle protein fractional synthetic rate occurs with intake of 20-30 g protein. This finding has led to the concept that there is a maximal anabolic response to protein intake with a meal, and that the normal amount of protein eaten with dinner will generally exceed the maximally-effective intake of protein. However, protein breakdown has not been taken into account when evaluating the anabolic response to protein intake. Protein anabolism occurs only when protein synthesis exceeds protein breakdown. Higher protein intakes when protein synthesis is maximized is characterized by suppressed protein breakdown and via that mechanism leads to a greater anabolic response. This explains why when net protein synthesis is measured, the relationship between amino acid availability and net gain remains linear, without any apparent plateau of effect at higher levels of availability. We conclude that there is no practical upper limit to the anabolic response to protein or amino acid intake in the context of a meal.

X Demographics

X Demographics

The data shown below were collected from the profiles of 193 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 277 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 3 1%
Brazil 2 <1%
United Kingdom 2 <1%
Germany 1 <1%
Australia 1 <1%
New Zealand 1 <1%
Spain 1 <1%
United States 1 <1%
Unknown 265 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 57 21%
Student > Bachelor 46 17%
Student > Ph. D. Student 38 14%
Researcher 27 10%
Other 22 8%
Other 45 16%
Unknown 42 15%
Readers by discipline Count As %
Sports and Recreations 55 20%
Medicine and Dentistry 49 18%
Agricultural and Biological Sciences 45 16%
Nursing and Health Professions 34 12%
Biochemistry, Genetics and Molecular Biology 19 7%
Other 27 10%
Unknown 48 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 159. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 January 2024.
All research outputs
#262,145
of 25,789,020 outputs
Outputs from Clinical Nutrition
#90
of 3,719 outputs
Outputs of similar age
#1,621
of 287,858 outputs
Outputs of similar age from Clinical Nutrition
#1
of 34 outputs
Altmetric has tracked 25,789,020 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,719 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.5. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,858 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.