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Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract

Overview of attention for book
Cover of 'Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Distal Esophageal Adenocarcinoma and Gastric Adenocarcinoma: Time for a Shared Research Agenda.
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    Chapter 2 Clonal Evolution of Stem Cells in the Gastrointestinal Tract.
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    Chapter 3 The Complex, Clonal, and Controversial Nature of Barrett's Esophagus.
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    Chapter 4 A New Pathologic Assessment of Gastroesophageal Reflux Disease: The Squamo-Oxyntic Gap.
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    Chapter 5 Diagnosis by Endoscopy and Advanced Imaging of Barrett's Neoplasia.
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    Chapter 6 Endoscopic Treatment of Early Barrett's Neoplasia: Expanding Indications, New Challenges.
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    Chapter 7 Definition, Derivation, and Diagnosis of Barrett's Esophagus: Pathological Perspectives.
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    Chapter 8 What Makes an Expert Barrett's Histopathologist?
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    Chapter 9 Staging Early Esophageal Cancer.
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    Chapter 10 Transcommitment: Paving the Way to Barrett's Metaplasia.
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    Chapter 11 Studying Cancer Evolution in Barrett's Esophagus and Esophageal Adenocarcinoma.
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    Chapter 12 Genomics of Esophageal Cancer and Biomarkers for Early Detection.
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    Chapter 13 Common Variants Confer Susceptibility to Barrett's Esophagus: Insights from the First Genome-Wide Association Studies.
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    Chapter 14 Endoluminal Diagnosis of Early Gastric Cancer and Its Precursors: Bridging the Gap Between Endoscopy and Pathology.
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    Chapter 15 Endoscopic Submucosal Dissection for Early Gastric Cancer: Getting It Right!
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    Chapter 16 The Japanese Viewpoint on the Histopathology of Early Gastric Cancer.
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    Chapter 17 Syndromic Gastric Polyps: At the Crossroads of Genetic and Environmental Cancer Predisposition.
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    Chapter 18 Histopathological, Molecular, and Genetic Profile of Hereditary Diffuse Gastric Cancer: Current Knowledge and Challenges for the Future.
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    Chapter 19 Helicobacter pylori, Cancer, and the Gastric Microbiota.
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    Chapter 20 Helicobacter pylori and Gastric Cancer: Timing and Impact of Preventive Measures.
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    Chapter 21 Genomics Study of Gastric Cancer and Its Molecular Subtypes.
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    Chapter 22 Recapitulating Human Gastric Cancer Pathogenesis: Experimental Models of Gastric Cancer.
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    Chapter 23 Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract
Attention for Chapter 21: Genomics Study of Gastric Cancer and Its Molecular Subtypes.
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Chapter title
Genomics Study of Gastric Cancer and Its Molecular Subtypes.
Chapter number 21
Book title
Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract
Published in
Advances in experimental medicine and biology, August 2016
DOI 10.1007/978-3-319-41388-4_21
Pubmed ID
27573784
Book ISBNs
978-3-31-941386-0, 978-3-31-941388-4
Authors

Siu Tsan Yuen, Suet Yi Leung

Editors

Marnix Jansen, Nicholas A. Wright

Abstract

Gastric cancer is a heterogeneous disease encompassing diverse morphological (intestinal versus diffuse) and molecular subtypes (MSI, EBV, TP53 mutation). Recent advances in genomic technology have led to an improved understanding of the driver gene mutational profile, gene expression, and epigenetic alterations that underlie each of the subgroups, with therapeutic implications in some of these alterations. There have been attempts to classify gastric cancers based on these genomic features, with an aim to improve prognostication and predict responsiveness to specific drug therapy. The eventual aims of these genomic studies are to develop deep biological insights into the carcinogenic pathway in each of these subtypes. Future large-scale drug screening strategies may then be able to link these genomic features to drug responsiveness, eventually leading to genome-guided personalized medicine with improved cure rates.

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X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 14%
Student > Doctoral Student 3 14%
Researcher 2 10%
Student > Ph. D. Student 2 10%
Student > Bachelor 1 5%
Other 4 19%
Unknown 6 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 24%
Agricultural and Biological Sciences 2 10%
Medicine and Dentistry 2 10%
Computer Science 2 10%
Veterinary Science and Veterinary Medicine 1 5%
Other 2 10%
Unknown 7 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 September 2016.
All research outputs
#18,468,369
of 22,884,315 outputs
Outputs from Advances in experimental medicine and biology
#3,315
of 4,952 outputs
Outputs of similar age
#257,857
of 336,871 outputs
Outputs of similar age from Advances in experimental medicine and biology
#53
of 81 outputs
Altmetric has tracked 22,884,315 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,952 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,871 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 81 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.

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