↓ Skip to main content

HPV Status of Oropharyngeal Cancer by Combination HPV DNA/p16 Testing: Biological Relevance of Discordant Results

Overview of attention for article published in Annals of Surgical Oncology, December 2012
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
28 Dimensions

Readers on

mendeley
31 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
HPV Status of Oropharyngeal Cancer by Combination HPV DNA/p16 Testing: Biological Relevance of Discordant Results
Published in
Annals of Surgical Oncology, December 2012
DOI 10.1245/s10434-012-2778-4
Pubmed ID
Authors

Angela Hong, Deanna Jones, Mark Chatfield, C. Soon Lee, Mei Zhang, Jonathan Clark, Michael Elliott, Gerald Harnett, Christopher Milross, Barbara Rose

Abstract

Human papillomavirus (HPV) causes up to 70 % of oropharyngeal cancers (OSCC). HPV positive OSCC has a more favorable outcome, thus HPV status is being used to guide treatment and predict outcome. Combination HPV DNA/p16(ink4) (p16) testing is commonly used for HPV status, but there are no standardized methods, scoring or interpretative criteria. The significance of discordant (HPV DNA positive/p16 negative and HPV DNA negative/p16 positive) cancers is controversial. In this study, 647 OSCCs from 10 Australian centers were tested for HPV DNA/p16 expression. Our aims are to determine p16 distribution by HPV DNA status to inform decisions on p16 scoring and to assess clinical significance of discordant cancers.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 13%
Student > Doctoral Student 4 13%
Librarian 3 10%
Professor 2 6%
Student > Bachelor 2 6%
Other 9 29%
Unknown 7 23%
Readers by discipline Count As %
Medicine and Dentistry 18 58%
Agricultural and Biological Sciences 2 6%
Social Sciences 2 6%
Biochemistry, Genetics and Molecular Biology 1 3%
Unknown 8 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 December 2012.
All research outputs
#15,258,711
of 22,689,790 outputs
Outputs from Annals of Surgical Oncology
#4,353
of 6,423 outputs
Outputs of similar age
#179,369
of 277,752 outputs
Outputs of similar age from Annals of Surgical Oncology
#30
of 46 outputs
Altmetric has tracked 22,689,790 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,423 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,752 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.