Title |
Clinical Predictors of Mortality and Cause of Death in Lymphangioleiomyomatosis: A Population-based Registry
|
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Published in |
Lung, September 2012
|
DOI | 10.1007/s00408-012-9419-3 |
Pubmed ID | |
Authors |
N. Oprescu, F. X. McCormack, S. Byrnes, B. W. Kinder |
Abstract |
Lymphangioleiomyomatosis (LAM) is a rare, progressive, frequently lethal cystic lung disease that almost exclusively affects women. Prognostic information in LAM has been limited by small numbers and heterogeneous study methodology. Early retrospective cohorts cited 5- and 10-year mortality of 40 and 80 %, respectively. More recently, mortality at 10 years has been estimated to be approximately 10-20 % from the onset of symptoms and 30 % at 10 years from the time of lung biopsy but varies widely in individual patients. Given the heterogeneous disease course, it would be useful to establish which clinical characteristics are associated with survival to develop prediction models for disease outcome. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Italy | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 3% |
Unknown | 59 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 13% |
Student > Master | 8 | 13% |
Student > Bachelor | 8 | 13% |
Researcher | 7 | 11% |
Student > Postgraduate | 6 | 10% |
Other | 11 | 18% |
Unknown | 13 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 27 | 44% |
Biochemistry, Genetics and Molecular Biology | 4 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Psychology | 2 | 3% |
Nursing and Health Professions | 2 | 3% |
Other | 9 | 15% |
Unknown | 15 | 25% |