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From gene switches to mammalian designer cells: present and future prospects

Overview of attention for article published in Trends in Biotechnology, December 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

blogs
1 blog
policy
1 policy source
twitter
8 X users
patent
8 patents
facebook
1 Facebook page

Citations

dimensions_citation
112 Dimensions

Readers on

mendeley
355 Mendeley
citeulike
4 CiteULike
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Title
From gene switches to mammalian designer cells: present and future prospects
Published in
Trends in Biotechnology, December 2012
DOI 10.1016/j.tibtech.2012.11.006
Pubmed ID
Authors

Simon Ausländer, Martin Fussenegger

Abstract

Nature has evolved a treasury of biological molecules that are logically connected to networks, enabling cells to maintain their functional integrity. Similar to electronic circuits, cells operate as information-processing systems that dynamically integrate and respond to distinct input signals. Synthetic biology aims to standardize and expand the natural toolbox of biological building blocks to engineer novel synthetic networks in living systems. Mammalian cells harboring integrated designer circuits could work as living biocomputers that execute predictable metabolic and therapeutic functions. This review presents design principles of mammalian gene circuits, highlights recent developments, and discusses future challenges and prospects.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 355 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 1%
Germany 2 <1%
France 2 <1%
United Kingdom 2 <1%
India 1 <1%
Israel 1 <1%
Austria 1 <1%
Belgium 1 <1%
Mexico 1 <1%
Other 2 <1%
Unknown 338 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 102 29%
Researcher 68 19%
Student > Master 49 14%
Student > Bachelor 40 11%
Other 16 5%
Other 42 12%
Unknown 38 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 139 39%
Biochemistry, Genetics and Molecular Biology 82 23%
Engineering 33 9%
Immunology and Microbiology 10 3%
Chemistry 9 3%
Other 40 11%
Unknown 42 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 May 2022.
All research outputs
#1,594,307
of 25,374,917 outputs
Outputs from Trends in Biotechnology
#190
of 2,856 outputs
Outputs of similar age
#13,447
of 286,292 outputs
Outputs of similar age from Trends in Biotechnology
#4
of 28 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,856 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.5. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 286,292 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.