Title |
Identification of 3′ gene ends using transcriptional and genomic conservation across vertebrates
|
---|---|
Published in |
BMC Genomics, December 2012
|
DOI | 10.1186/1471-2164-13-708 |
Pubmed ID | |
Authors |
Marcos Morgan, Alessandra Iaconcig, Andrés Fernando Muro |
Abstract |
In higher eukaryotes, gene expression is regulated at different levels. In particular, 3'UTRs play a central role in translation, stability and subcellular localization of transcripts. In recent years, the development of high throughput sequencing techniques has facilitated the acquisition of transcriptional data at a genome wide level. However, annotation of the 3' ends of genes is still incomplete, thus limiting the interpretation of the data generated. For example, we have previously reported two different genes, ADD2 and CPEB3, with conserved 3'UTR alternative isoforms not annotated in the current versions of Ensembl and RefSeq human databases. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 67% |
France | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 5% |
Australia | 1 | 5% |
Unknown | 19 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 33% |
Student > Ph. D. Student | 6 | 29% |
Student > Bachelor | 2 | 10% |
Student > Master | 2 | 10% |
Student > Doctoral Student | 1 | 5% |
Other | 2 | 10% |
Unknown | 1 | 5% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 9 | 43% |
Biochemistry, Genetics and Molecular Biology | 8 | 38% |
Medicine and Dentistry | 1 | 5% |
Unknown | 3 | 14% |