Title |
Peer-Education Intervention to Reduce Injection Risk Behaviors Benefits High-Risk Young Injection Drug Users: A Latent Transition Analysis of the CIDUS 3/DUIT Study
|
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Published in |
AIDS and Behavior, November 2012
|
DOI | 10.1007/s10461-012-0373-0 |
Pubmed ID | |
Authors |
Mary E. Mackesy-Amiti, Lorna Finnegan, Lawrence J. Ouellet, Elizabeth T. Golub, Holly Hagan, Sharon M. Hudson, Mary H. Latka, Richard S. Garfein |
Abstract |
We analyzed data from a large randomized HIV/HCV prevention intervention trial with young injection drug users (IDUs) conducted in five U.S. cities. The trial compared a peer education intervention (PEI) with a time-matched, attention control group. Applying categorical latent variable analysis (mixture modeling) to baseline injection risk behavior data, we identified four distinct classes of injection-related HIV/HCV risk: low risk, non-syringe equipment-sharing, moderate-risk syringe-sharing, and high-risk syringe-sharing. The trial participation rate did not vary across classes. We conducted a latent transition analysis using trial baseline and 6-month follow-up data, to test the effect of the intervention on transitions to the low-risk class at follow-up. Adjusting for gender, age, and race/ethnicity, a significant intervention effect was found only for the high-risk class. Young IDU who exhibited high-risk behavior at baseline were 90% more likely to be in the low-risk class at follow-up after the PEI intervention, compared to the control group. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 2 | 50% |
Canada | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Unknown | 117 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 22 | 18% |
Researcher | 21 | 18% |
Student > Ph. D. Student | 16 | 13% |
Student > Bachelor | 7 | 6% |
Student > Doctoral Student | 6 | 5% |
Other | 21 | 18% |
Unknown | 26 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 24 | 20% |
Nursing and Health Professions | 20 | 17% |
Social Sciences | 19 | 16% |
Psychology | 10 | 8% |
Agricultural and Biological Sciences | 2 | 2% |
Other | 11 | 9% |
Unknown | 33 | 28% |