| Title |
Delayed accumulation of intestinal coliform bacteria enhances life span and stress resistance in Caenorhabditis elegans fed respiratory deficient E. coli
|
|---|---|
| Published in |
BMC Microbiology, December 2012
|
| DOI | 10.1186/1471-2180-12-300 |
| Pubmed ID | |
| Authors |
Fernando Gomez, Gabriela C Monsalve, Vincent Tse, Ryoichi Saiki, Emily Weng, Laura Lee, Chandra Srinivasan, Alison R Frand, Catherine F Clarke |
| Abstract |
Studies with the nematode model Caenorhabditis elegans have identified conserved biochemical pathways that act to modulate life span. Life span can also be influenced by the composition of the intestinal microbiome, and C. elegans life span can be dramatically influenced by its diet of Escherichia coli. Although C. elegans is typically fed the standard OP50 strain of E. coli, nematodes fed E. coli strains rendered respiratory deficient, either due to a lack coenzyme Q or the absence of ATP synthase, show significant life span extension. Here we explore the mechanisms accounting for the enhanced nematode life span in response to these diets. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Spain | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 33% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 161 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Hungary | 1 | <1% |
| Denmark | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 158 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 49 | 30% |
| Student > Ph. D. Student | 25 | 16% |
| Researcher | 23 | 14% |
| Student > Master | 15 | 9% |
| Other | 6 | 4% |
| Other | 19 | 12% |
| Unknown | 24 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 58 | 36% |
| Biochemistry, Genetics and Molecular Biology | 39 | 24% |
| Immunology and Microbiology | 10 | 6% |
| Neuroscience | 4 | 2% |
| Chemistry | 4 | 2% |
| Other | 18 | 11% |
| Unknown | 28 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 January 2013.
All research outputs
#15,557,505
of 23,881,329 outputs
Outputs from BMC Microbiology
#1,652
of 3,286 outputs
Outputs of similar age
#181,062
of 285,713 outputs
Outputs of similar age from BMC Microbiology
#49
of 94 outputs
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