| Title |
Gene-Environment Interaction in the Etiology of Mathematical Ability Using SNP Sets
|
|---|---|
| Published in |
Behavior Genetics, October 2010
|
| DOI | 10.1007/s10519-010-9405-6 |
| Pubmed ID | |
| Authors |
Sophia J. Docherty, Yulia Kovas, Robert Plomin |
| Abstract |
Mathematics ability and disability is as heritable as other cognitive abilities and disabilities, however its genetic etiology has received relatively little attention. In our recent genome-wide association study of mathematical ability in 10-year-old children, 10 SNP associations were nominated from scans of pooled DNA and validated in an individually genotyped sample. In this paper, we use a 'SNP set' composite of these 10 SNPs to investigate gene-environment (GE) interaction, examining whether the association between the 10-SNP set and mathematical ability differs as a function of ten environmental measures in the home and school in a sample of 1888 children with complete data. We found two significant GE interactions for environmental measures in the home and the school both in the direction of the diathesis-stress type of GE interaction: The 10-SNP set was more strongly associated with mathematical ability in chaotic homes and when parents are negative. |
Mendeley readers
The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| United Kingdom | 2 | 2% |
| Netherlands | 1 | 1% |
| Italy | 1 | 1% |
| Brazil | 1 | 1% |
| Mexico | 1 | 1% |
| Canada | 1 | 1% |
| Unknown | 84 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 19% |
| Student > Master | 14 | 15% |
| Student > Doctoral Student | 14 | 15% |
| Researcher | 9 | 10% |
| Student > Postgraduate | 7 | 8% |
| Other | 18 | 19% |
| Unknown | 13 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 44 | 47% |
| Agricultural and Biological Sciences | 10 | 11% |
| Medicine and Dentistry | 4 | 4% |
| Social Sciences | 4 | 4% |
| Engineering | 3 | 3% |
| Other | 7 | 8% |
| Unknown | 21 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2012.
All research outputs
#4,628,752
of 22,691,736 outputs
Outputs from Behavior Genetics
#241
of 908 outputs
Outputs of similar age
#20,635
of 99,262 outputs
Outputs of similar age from Behavior Genetics
#2
of 10 outputs
Altmetric has tracked 22,691,736 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 908 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 99,262 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 8 of them.